Ignite Creation Date:
2024-05-05 @ 6:50 PM
Last Modification Date:
2024-10-26 @ 9:37 AM
Study NCT ID:
NCT00554801
Status:
COMPLETED
Last Update Posted:
2018-08-10
First Post:
2007-11-05
Brief Title:
Central Auditory Processing Disorders Associated With Blast Exposure
Sponsor:
VA Office of Research and Development
Organization:
VA Office of Research and Development
Study Overview
Official Title:
Central Auditory Processing Disorders Associated With Blast Exposure
Status:
COMPLETED
Status Verified Date:
2018-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The incidence of central auditory dysfunction in war fighters who are exposed to high-explosive blasts while serving in combat have not been clearly determined The objectives of this study are to determine whether central auditory processing CAP disorders are associated with exposure to high-explosive blasts This study will also examine the incidence magnitude and timing of spontaneous recovery of CAP function from blast exposure The information provided by this study will help guide clinicians in both the military and VA health care systems regarding the likelihood of central auditory processing disorders in soldiers returning from deployment and suggest some clinical rehabilitative strategies for the treatment of these patients with CAP deficits
Detailed Description:
The incidence and nature of central auditory dysfunction in combat soldiers who are exposed to high-explosive blasts have not been determined Using a battery of behavioral and neurophysiological auditory tests we propose to evaluate central auditory function in soldiers who recently have been exposed to explosive blasts while deployed in Iraq or Afghanistan In collaboration with the Army Audiology Speech Center at Walter Reed Army Medical Center WRAMC the research will be coordinated at the National Center for Rehabilitative Auditory Research NCRAR at the Portland VA Medical Center and data collection will take place both at the NCRAR and at WRAMC The study objectives are to determine if specific central auditory processing disorders are often associated with exposure to high-explosive blasts and if these disorders spontaneously recover or remain over time One hundred patients who have suffered a blast exposure but have either no brain damage or mild traumatic brain injury TBI will be recruited at WRAMC to participate in this research study A battery of central auditory processing tests will be administered to participants as soon as possible after their arrival at WRAMC Patients who demonstrate aspects of central auditory processing disorder will be invited to participate in further testing nine to twelve months later Those subjects will be brought to the NCRAR at the Portland VA Medical Center or will return to WRAMC for two days of auditory testing where they will undergo the same battery of tests administered initially Control subjects who do not have a history of blast exposure and who are matched in age gender and audiometric configuration with the experimental subjects will also be tested at the NCRAR site Data extracted by interview and from medical records including details of the blast exposure scores on overall tests of brain function administered by the WRAMC TBI team presence or absence of post traumatic stress disorder as well as self-report questionnaires regarding quality of life presence of tinnitus andor balance problems will be used in the interpretation of results
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None