Ignite Creation Date:
2024-05-06 @ 7:20 PM
Last Modification Date:
2024-10-26 @ 3:05 PM
Study NCT ID:
NCT05978011
Status:
COMPLETED
Last Update Posted:
2023-08-07
First Post:
2023-07-27
Brief Title:
2014TP001 - Assessing the Biology of the Injured Lung - Version 1
Sponsor:
Manchester University NHS Foundation Trust
Organization:
Manchester University NHS Foundation Trust
Study Overview
Official Title:
Assessing the Biology of the Injured Lung - Version 1
Status:
COMPLETED
Status Verified Date:
2023-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Respiratory diseases are very common and are the third leading cause of death in England As such there is strong interest in understanding how respiratory disease occurs
This study intends to understand the changes that occur within diseasedinjured lungs obtained from humans The end goal of this will be to create new drugs to help treat these disorders
Diseased lungs will be obtained from patients receiving a lung transplant Lungs will either be placed onto a heart-lung machine or surgically cut in order to create a model of the lung that can be used experimentally in the laboratory Using a heart-lung machine lungs can be maintained outside of the human body for a maximum of 12 hours allowing the direct assessment of the organ Using this procedure we aim to understand the processes that occur within a disease as well as during repair Using the model of the lung we will look at how the bodys immune system interacts within a diseased lung
This study intends to understand the changes that occur within diseasedinjured lungs obtained from humans The end goal of this will be to create new drugs to help treat these disorders
Diseased lungs will be obtained from patients receiving a lung transplant Lungs will either be placed onto a heart-lung machine or surgically cut in order to create a model of the lung that can be used experimentally in the laboratory Using a heart-lung machine lungs can be maintained outside of the human body for a maximum of 12 hours allowing the direct assessment of the organ Using this procedure we aim to understand the processes that occur within a disease as well as during repair Using the model of the lung we will look at how the bodys immune system interacts within a diseased lung
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None