Ignite Creation Date:
2024-05-06 @ 7:19 PM
Last Modification Date:
2024-10-26 @ 3:04 PM
Study NCT ID:
NCT05961722
Status:
COMPLETED
Last Update Posted:
2023-07-27
First Post:
2023-07-13
Brief Title:
Preoperative Intravenous Fluid Type and Postoperative Nausea
Sponsor:
Ankara Etlik City Hospital
Organization:
Ankara Etlik City Hospital
Study Overview
Official Title:
The Effect of Choosing of Preoperative Intravenous Fluid Type on the Postoperative Nausea Vomiting Anxiety and Pain After Laparoscopic Cholecystectomy
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study it was aimed to investigate the relationship between postoperative nausea and vomiting anxiety levels and pain scores in the postoperative period according to dosing and choosing of intravenous fluid type that the patients received in the preoperative period
Detailed Description:
Fluid management is an integral and important part of perioperative treatment In order to prevent organ damage a key components of assuring adequate organ perfusion is to provide adequate volume and appropriate fluid Types of the fluids amount of the fluid given and timing of the administration are the main topics that determine the fluid management strategy Colloids eg albumin or fresh frozen plasma FFP and crystalloids eg ringer lactate isotonic 5 dextrose are types of intravenous fluids that are used for fluid replacement apart from blood transfusion Crystalloids are low-cost salt solutions with small molecules which can move around easily when injected into the body
There are studies reporting that fluid therapy applied in the preoperative period reduces gastric acid secretion and reduces stomach movements and nausea and vomiting In addition there are studies reporting that fluids given in the preoperative period have a positive effect on anxiety levels by reducing the feeling of hunger and thirst in patients There are studies reporting that fluid therapy reduces ATP destruction and oxidative stress which contributes to the reduction of pain levels
90 ASA I-II patients who will undergo laparoscopic cholecystectomy surgery will be included in the study and will be divided into three equal groups Patients in Group 1 were administered 400 ml 09 saline infusion within 30 minutes 2 hours before surgery Patients in Group 2 were infused with 400 ml 5 Dextrose at the same infusion rate In groups 1 and 2 10 mlkgh 09 saline infusion was applied during the intraoperative period Patients in Group 3 were administered 200 ml dextrose infusion in the preoperative period and 200 ml dextrose infusion in the intraoperative period 09 saline infusion was applied so that the total intraoperative fluid volume was the same as in the other groups
Postoperative nausea and vomiting PONV within 24 hours was compared between groups by PONV score Other outcomes were the antiemetic drugs needed The NRS Score The State-Trait Anxiety Inventory additional analgesic drug requirement
In this study it was aimed to investigate the relationship between postoperative nausea and vomiting anxiety levels and pain scores in the postoperative period according to dosing and choosing of intravenous fluid type that the patients received in the preoperative period
There are studies reporting that fluid therapy applied in the preoperative period reduces gastric acid secretion and reduces stomach movements and nausea and vomiting In addition there are studies reporting that fluids given in the preoperative period have a positive effect on anxiety levels by reducing the feeling of hunger and thirst in patients There are studies reporting that fluid therapy reduces ATP destruction and oxidative stress which contributes to the reduction of pain levels
90 ASA I-II patients who will undergo laparoscopic cholecystectomy surgery will be included in the study and will be divided into three equal groups Patients in Group 1 were administered 400 ml 09 saline infusion within 30 minutes 2 hours before surgery Patients in Group 2 were infused with 400 ml 5 Dextrose at the same infusion rate In groups 1 and 2 10 mlkgh 09 saline infusion was applied during the intraoperative period Patients in Group 3 were administered 200 ml dextrose infusion in the preoperative period and 200 ml dextrose infusion in the intraoperative period 09 saline infusion was applied so that the total intraoperative fluid volume was the same as in the other groups
Postoperative nausea and vomiting PONV within 24 hours was compared between groups by PONV score Other outcomes were the antiemetic drugs needed The NRS Score The State-Trait Anxiety Inventory additional analgesic drug requirement
In this study it was aimed to investigate the relationship between postoperative nausea and vomiting anxiety levels and pain scores in the postoperative period according to dosing and choosing of intravenous fluid type that the patients received in the preoperative period
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None