Ignite Creation Date:
2024-05-06 @ 7:19 PM
Last Modification Date:
2024-10-26 @ 3:04 PM
Study NCT ID:
NCT05964920
Status:
RECRUITING
Last Update Posted:
2023-11-13
First Post:
2023-06-16
Brief Title:
Does Human Skeletal Muscle Possess an Epigenetic Memory of Testosterone
Sponsor:
Norwegian School of Sport Sciences
Organization:
Norwegian School of Sport Sciences
Study Overview
Official Title:
Does Human Skeletal Muscle Possess an Epigenetic Memory of Testosterone
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This projects primary aim of this double-blinded randomised placebo-controlled trial is to investigate whether short-term testosterone administration - resistance exercise training induces a muscle memory response that can lead to longer-lasting benefits in aged human skeletal muscle
The investigators will provide older men with the anabolic hormone testosterone or placebo with or without resistance training followed by a period of testosterone abstinence and detraining followed by a subsequent repeated period of resistance training retraining This will help determine if earlier encounters with short-term testosterone administration can be remembered and if adaptation to later retraining can be enhanced as a consequence of encountering testosterone earlier
The investigators will provide older men with the anabolic hormone testosterone or placebo with or without resistance training followed by a period of testosterone abstinence and detraining followed by a subsequent repeated period of resistance training retraining This will help determine if earlier encounters with short-term testosterone administration can be remembered and if adaptation to later retraining can be enhanced as a consequence of encountering testosterone earlier
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None