Ignite Creation Date:
2024-05-05 @ 11:21 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00002317
Status:
COMPLETED
Last Update Posted:
2005-06-24
First Post:
1999-11-02
Brief Title:
A Study of Trimetrexate Plus Leucovorin in Children With Pneumocystis Carinii Pneumonia
Sponsor:
US Bioscience
Organization:
NIH AIDS Clinical Trials Information Service
Study Overview
Official Title:
A Study of Neutrexin Trimetrexate Glucuronate With Leucovorin Protection for Pediatric Patients Ages 2-12 With Pneumocystis Carinii Pneumonia
Status:
COMPLETED
Status Verified Date:
1993-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To evaluate the safety and efficacy of trimetrexate glucuronate with leucovorin protection in pediatric patients with Pneumocystis carinii pneumonia PCP who are refractory to or have demonstrated severe or life-threatening toxicities to standard therapies eg TMPSMX or parenteral pentamidine
Detailed Description:
Patients receive intravenous infusions of trimetrexate glucuronate and leucovorin for 21 days Leucovorin is continued for 3 additional days after discontinuation of trimetrexate glucuronate Patients are followed for 1 month
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| TMTX 0015 | None | None | None |