Ignite Creation Date:
2024-05-06 @ 7:19 PM
Last Modification Date:
2024-10-26 @ 3:04 PM
Study NCT ID:
NCT05961488
Status:
RECRUITING
Last Update Posted:
2024-03-06
First Post:
2023-07-18
Brief Title:
Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac Arrest
Sponsor:
CHU de Reims
Organization:
CHU de Reims
Study Overview
Official Title:
Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac Arrest
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PERFECCT
Brief Summary:
Out-of-hospital cardiac arrest OHCA has multiple etiologies In the absence of ST-elevation myocardial infarction percutaneous coronary intervention PCI is delayed This study aims to determine the diagnostic accuracy of Coronary Calcium Score CCS and Coronary CT Angiogram CCTA to rule out a coronary artery disease CAD in the first days after an OHCA
Detailed Description:
Each year 50000 out-of-hospital cardiac arrest OHCA occur in France Acute myocardial infarction AMI is one of the most frequent etiology of OHCA When a cardiac arrest is due to a ST-elevation myocardial infarction STEMI a percutaneous coronary intervention PCI is realized in emergency However without ST-elevation PCI timing is unclear 2020 European Society Recommandations suggest that PCI should not be realized in emergency based on Lemkes and al clinical trial But there is scarce evidence about the exact timing to realize PCI Electrocardiogram troponin level and echocardiography are unprecise to rule-out an ischemic etiology of cardiac arrest
A brain CT-scan and a CT-pulmonary angiogram are recommended in first place to identify the etiology of the cardiac arrest if there is no ST-elevation nor obvious causes Nevertheless in the absence of scanographic abnormality a differed coronary angiogram should be realized
We suggest that coronary CT angiogram CCTA and coronary calcium score CCS are feasible in the first days of hospitalization and could rule-out a coronary artery disease CAD The aim of the study is to avoid an invasive coronary exploration and to have a quick answer about anti-thrombotic treatments management
A brain CT-scan and a CT-pulmonary angiogram are recommended in first place to identify the etiology of the cardiac arrest if there is no ST-elevation nor obvious causes Nevertheless in the absence of scanographic abnormality a differed coronary angiogram should be realized
We suggest that coronary CT angiogram CCTA and coronary calcium score CCS are feasible in the first days of hospitalization and could rule-out a coronary artery disease CAD The aim of the study is to avoid an invasive coronary exploration and to have a quick answer about anti-thrombotic treatments management
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None