Ignite Creation Date:
2024-05-06 @ 7:18 PM
Last Modification Date:
2024-10-26 @ 3:04 PM
Study NCT ID:
NCT05965115
Status:
RECRUITING
Last Update Posted:
2023-08-01
First Post:
2023-06-30
Brief Title:
The China M-protein Screening Project in First-degree Relatives of Myeloma Patient - The CHAPERONE Study
Sponsor:
Shanghai Zhongshan Hospital
Organization:
Shanghai Zhongshan Hospital
Study Overview
Official Title:
The China Monoclonal Gammopathy Screening Project in First-degree Relatives of Patients With Multiple Myeloma CHAPERONE --A Multicenter Observational Study
Status:
RECRUITING
Status Verified Date:
2023-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CHAPERONE
Brief Summary:
The goal of the China Monoclonal Gammopathy Screening Project in First-degree Relatives of Patients With Multiple Myeloma CHAPERONE study is to assess the clinical significance of screening for monoclonal gammopathy M-protein in first-degree relatives of patients with multiple myeloma in China population and establish a prospective cohort of individuals with monoclonal gammopathy of undetermined significance MGUS a precursor conditions to multiple myeloma We will study these patients as a means to identify risk factors for progression to symptomatic multiple myeloma
Detailed Description:
The CHAPERONE study aims to assess the clinical significance of screening for monoclonal gammopathy in first-degree relatives of patients with multiple myeloma in China
The main objectives it aims to answer are
Main research objectives To study the prevalence of MGUS the time of disease progression and its influencing factors in first-degree relatives of multiple myeloma patients in China
Secondary study objective To explore the clinicalgenomicepigenetic features survival and quality of life of MGUS patients in first-degree relatives of multiple myeloma patients in China
All participants will receive M-protein screening by serum electrophoresis Individuals with detected M-protein will undergo further diagnostic tests and patients with MGUS will be carefully assessed and followed up
The main objectives it aims to answer are
Main research objectives To study the prevalence of MGUS the time of disease progression and its influencing factors in first-degree relatives of multiple myeloma patients in China
Secondary study objective To explore the clinicalgenomicepigenetic features survival and quality of life of MGUS patients in first-degree relatives of multiple myeloma patients in China
All participants will receive M-protein screening by serum electrophoresis Individuals with detected M-protein will undergo further diagnostic tests and patients with MGUS will be carefully assessed and followed up
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None