Ignite Creation Date:
2024-05-06 @ 7:16 PM
Last Modification Date:
2024-10-26 @ 3:03 PM
Study NCT ID:
NCT05953883
Status:
RECRUITING
Last Update Posted:
2023-07-20
First Post:
2023-06-21
Brief Title:
PROTEOGENOMIC SIGNATURES ANALYSIS IN OVARIAN CANCER
Sponsor:
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Organization:
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study Overview
Official Title:
PROTEOGENOMIC SIGNATURES ANALYSIS IN OVARIAN CANCER LONGITUDINAL MODIFICATION ON TUMOR TISSUE BEFORE AND AFTER PLATINUM-BASED NEOADJUVANT CHEMOTHERAPY
Status:
RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PROGENITOR
Brief Summary:
Proteogenomic analysis to detect individual platinum-induced modifications on tumor tissue of HGSC according to chemotherapy response score CRS using a combined approach of High resolution liquid chromatography mass Spectrometry based platform HR-LC-MSMS and advanced immunometric methods on illumine platform multiple supervised machine learning algorithms will be used to discover proteogenomic signatures and biological processes associated with platinum modification during the neoadjuvant chemotherapy treatment These results contribute to precision medicine by building an accurate proteogenomic profile of ovarian cancer in order to better understand the underlying mechanisms of different chemotherapy response among affected patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None