Ignite Creation Date:
2024-05-06 @ 7:15 PM
Last Modification Date:
2024-10-26 @ 3:03 PM
Study NCT ID:
NCT05947513
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-07-17
First Post:
2023-06-21
Brief Title:
Concomitant Curcumin Palliative Radiotherapy in Advanced Cervical Cancer Trial
Sponsor:
Addis Ababa University
Organization:
Addis Ababa University
Study Overview
Official Title:
Feasibility Safety and Efficacy of Concomitant Curcumin in Patients Undergoing Palliative Radiotherapy for FIGO Stage IIIB-IVA Cervical Cancer An Open-label Pilot Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CuPRAC
Brief Summary:
The goal of this clinical trial is to test curcumin as an adjunct treatment in patients with cervical cancer receiving standard-of-care palliative radiation The main questions it aims to answer are
Is adding curcumin to standard-of-care palliative radiotherapy of cervical cancer patients safe
Does adding curcumin to standard-of-care palliative radiotherapy of cervical cancer patients improve therapeutic responses
How much curcumin is absorbed into the body and how long will it stay in the body
Participants will
Take two 500 mg curcumin capsules twice per day for 4-6 weeks in addition to the prescribed palliative radiotherapy
Provide blood and urine samples for laboratory tests
Provide blood samples to measure curcumin levels in their body
Obtain CT-scan to measure their tumor response
Complete questioners to measure improvements to their quality of life if any
Is adding curcumin to standard-of-care palliative radiotherapy of cervical cancer patients safe
Does adding curcumin to standard-of-care palliative radiotherapy of cervical cancer patients improve therapeutic responses
How much curcumin is absorbed into the body and how long will it stay in the body
Participants will
Take two 500 mg curcumin capsules twice per day for 4-6 weeks in addition to the prescribed palliative radiotherapy
Provide blood and urine samples for laboratory tests
Provide blood samples to measure curcumin levels in their body
Obtain CT-scan to measure their tumor response
Complete questioners to measure improvements to their quality of life if any
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None