Ignite Creation Date:
2024-05-06 @ 7:14 PM
Last Modification Date:
2024-10-26 @ 3:03 PM
Study NCT ID:
NCT05945043
Status:
RECRUITING
Last Update Posted:
2024-02-28
First Post:
2023-06-07
Brief Title:
Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion
Sponsor:
Guys and St Thomas NHS Foundation Trust
Organization:
Guys and St Thomas NHS Foundation Trust
Study Overview
Official Title:
Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion COSINE
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
COSINE
Brief Summary:
The aim of this study is to better understand the relationship between pleural effusions and breathlessness in patients with unilateral pleural effusions and breathlessness who require pleural fluid removal for its management
Detailed Description:
This study will involve 124 adult patients who are breathlessness with pleural effusions They will be recruited from a single UK centre over an 18-month period
After being informed about the study all patients giving written informed consent will undergo a baseline assessment when they first come to have their fluid drained The investigators will record information about them and their disease The investigators will take measurements of their breathlessness their breathing muscles and the electrical activity from the brain to those muscles These will be taken at the start and end of drainage as well as 1 day and 7 days after The investigators will use this information to look for links between the effect of pleural effusions and its removal on the electrical activities of the breathing muscles and patients breathlessness
After being informed about the study all patients giving written informed consent will undergo a baseline assessment when they first come to have their fluid drained The investigators will record information about them and their disease The investigators will take measurements of their breathlessness their breathing muscles and the electrical activity from the brain to those muscles These will be taken at the start and end of drainage as well as 1 day and 7 days after The investigators will use this information to look for links between the effect of pleural effusions and its removal on the electrical activities of the breathing muscles and patients breathlessness
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None