Ignite Creation Date:
2024-05-06 @ 7:14 PM
Last Modification Date:
2024-10-26 @ 3:03 PM
Study NCT ID:
NCT05947370
Status:
COMPLETED
Last Update Posted:
2023-07-17
First Post:
2023-06-04
Brief Title:
Berberine on the Secretion of Incretin
Sponsor:
Beijing Tongren Hospital
Organization:
Beijing Tongren Hospital
Study Overview
Official Title:
The Effect of Berberine on the Secretion of Incretin in Normal Man
Status:
COMPLETED
Status Verified Date:
2023-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Berberine BBR is the main active ingredient of the ancient Chinese herb medicine Coptis The hypoglycemic effect of BBR has been demonstrated in numerous studies Although BBR is safe and effective in the treatment of diabetes its exact hypoglycemic mechanism is still unclear Jin-Kui Yang found that BBR can promote GLP-1 secretion from intestinal L cells in mice in vitro and in vivo thereby achieving the effect of lowering blood glucose but it is still unknown whether BBR can promote incretin secretion in humans In this study investigators plan to examine the effect of BBR on secretion of incretin in human
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None