Viewing Study NCT05947279



Ignite Creation Date: 2024-05-06 @ 7:14 PM
Last Modification Date: 2024-10-26 @ 3:03 PM
Study NCT ID: NCT05947279
Status: RECRUITING
Last Update Posted: 2024-05-21
First Post: 2023-06-30

Brief Title: Examining Lateralized Aspects of Motor Control Using Non-invasive Neural Stimulation
Sponsor: Virginia Commonwealth University
Organization: Virginia Commonwealth University

Study Overview

Official Title: Examining Lateralized Aspects of Motor Control Using Non-invasive Neural Stimulation
Status: RECRUITING
Status Verified Date: 2024-05
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Motor adaptation and generalization are believed to occur via the integration of various forms of sensory feedback for a congruent representation of the bodys position in space along with estimation of inertial properties of the limb segments for accurate specification of movement Thus motor adaptation is often studied within curated environments incorporating a mis-match between different sensory systems ie a visual field shift via prism googles or a visuomotor rotation via virtual reality environment and observing how motor plans change based on this mis-match However these adaptations are environment-specific and show little generalization outside of their restricted experimental setup There remains a need for motor adaptation research that demonstrates motor learning that generalizes to other environments and movement types This work could then inform physical and occupational therapy neurorehabilitation interventions targeted at addressing motor deficits
Detailed Description: Voluntary movement and sensory perception are fundamental aspects of the human experience Senses such as visual and proprioceptive feedback inform movement by continuously providing the central nervous system with information on limb location movement error and task performance However the specific mechanisms behind how different forms of sensory information are used to adapt and generalize movement remain poorly understood

Motor adaptation or the modification of movement based on error feedback Martin et al 1996 is often elicited during rehabilitation but must be generalized to functional performance such as activities of daily living in order to successfully rehabilitate motor deficits following stroke Motor adaptation and generalization are believed to occur via the integration of various forms of sensory feedback for a congruent representation of the bodys position in space along with estimation of inertial properties of the limb segments for accurate specification of movement Thus motor adaptation is often studied within curated environments incorporating a mis-match between different sensory systems ie a visual field shift via prism googles or a visuomotor rotation via virtual reality environment and observing how motor plans change based on this mis-match However these adaptations are environment-specific and show little generalization outside of their restricted experimental setup There remains a need for motor adaptation research that demonstrates motor learning that generalizes to other environments and movement types This work could then inform physical and occupational therapy neurorehabilitation interventions targeted at addressing motor deficits

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None