Ignite Creation Date:
2024-05-06 @ 7:12 PM
Last Modification Date:
2024-10-26 @ 3:02 PM
Study NCT ID:
NCT05921370
Status:
COMPLETED
Last Update Posted:
2024-01-31
First Post:
2023-06-18
Brief Title:
Silodosin in Retrograde Intrarenal Surgery
Sponsor:
Ain Shams University
Organization:
Ain Shams University
Study Overview
Official Title:
Effect of Perioperative Silodosin on Ureteric Dilatation in Retrograde Intrarenal Surgery
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Selective alpha-blockers have been used for the treatment of ureteric stones as medical expulsive therapy MET Recently they have been successfully used in passive ureteric dilatation before semirigid ureteroscopy This study enables us to know the role of silodosin in ureteric dilatation to facilitate ureteral access sheath placement in Retrograde Intrarenal Surgery with flexible ureteroscopy
Detailed Description:
The ureteral access sheaths UAS used during Retrograde Intrarenal Surgery RIRS were produced for easy access to the upper urinary tract The main advantages of UAS are providing repetitive access to the ureteral and collecting duct system decreasing intrarenal pressure preventing bleeding-related distortion of vision by the acceleration of liquid flow and eventually contributing toward the protection of the flexible device
Nevertheless there might be certain challenges during UAS placement There are also risks such as ureteral injury and the occurrence of ureteral stricture in the long term However considering the benefitrisk balance RIRS is routinely performed in many clinics because of the ease provided by UAS
Some problems might occur during the placement of UAS whose diameters vary between 95 and 14 Fr In cases where UAS cannot be placed manipulations can be used such as ureteral balloon dilatation providing access through a rigid ureteroscope with a guide wire or dilatation with the inner sheath of the UAS which may vary depending on the amount of personal experience Despite such manipulations if UAS placement is still unsuccessful it is always more logical to place a double-J stent enables passive dilatation and postpone RIRS until the second operation
This study will examine whether intramural ureteral resistance can be reduced or not and whether UAS placement can be facilitated using silodosin or not
Nevertheless there might be certain challenges during UAS placement There are also risks such as ureteral injury and the occurrence of ureteral stricture in the long term However considering the benefitrisk balance RIRS is routinely performed in many clinics because of the ease provided by UAS
Some problems might occur during the placement of UAS whose diameters vary between 95 and 14 Fr In cases where UAS cannot be placed manipulations can be used such as ureteral balloon dilatation providing access through a rigid ureteroscope with a guide wire or dilatation with the inner sheath of the UAS which may vary depending on the amount of personal experience Despite such manipulations if UAS placement is still unsuccessful it is always more logical to place a double-J stent enables passive dilatation and postpone RIRS until the second operation
This study will examine whether intramural ureteral resistance can be reduced or not and whether UAS placement can be facilitated using silodosin or not
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None