Viewing Study NCT05918510



Ignite Creation Date: 2024-05-06 @ 7:09 PM
Last Modification Date: 2024-10-26 @ 3:01 PM
Study NCT ID: NCT05918510
Status: RECRUITING
Last Update Posted: 2023-10-10
First Post: 2023-03-29

Brief Title: Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus
Sponsor: Regina Elena Cancer Institute
Organization: Regina Elena Cancer Institute

Study Overview

Official Title: Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus
Status: RECRUITING
Status Verified Date: 2023-06
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Based on the evidence summarized in the introduction the clinician hypothesize that the detection of the presence and expression of HPV-DNA certain miRNAs and a certain mutational profile in the tissues and biological fluids of these patients may have important prognostic and diagnostic value not only in HPV-related OPSCCs but also in HPV occult T Accordingly this study aims to aim to better characterize their potential as biomarkers and to detect the possibility of their their use to implement the sensitivity and specificity of radiological methodologies PET-CT and MRI already in use in clinical practice for monitoring disease progression in this specific subgroup Finally by using the collected material to generate organoids and Patient Derived Xenograft PDX the study also aims to identify possible new molecular drugs which could solve the problem of resistance to radiochemotherapy
Detailed Description: None

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None