Ignite Creation Date:
2024-05-06 @ 7:08 PM
Last Modification Date:
2024-10-26 @ 3:01 PM
Study NCT ID:
NCT05909319
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-06-18
First Post:
2023-05-29
Brief Title:
Identification and Verification of Neutrophil Extracellular Trap Net Related Markers in Acute-on-chronic Liver Failure
Sponsor:
First Affiliated Hospital of Wenzhou Medical University
Organization:
First Affiliated Hospital of Wenzhou Medical University
Study Overview
Official Title:
Identification and Verification of Neutrophil Extracellular Trap Net Related Markers in Acute-on-chronic Liver Failure
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Acute-on-chronic liver failure ACLF refers to the acute deterioration of liver function in patients with chronic liver disease Neutrophils are a major component of the innate immune system and previous studies have revealed enhanced production of neutrophil extracellular traps NETs in ACLF However there is still a lack of systematic research on the correlation between NETs and the prognosis of ACLF We screened NETs related biomarkers through bioinformatics analysis which play an important role in the diagnosis of ACLF This study will explore whether these NETs related biomarkers also play an important role in the prognosis of ACLF and further investigate their role in the pathogenesis of ACLF
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None