Ignite Creation Date:
2024-05-06 @ 7:08 PM
Last Modification Date:
2024-10-26 @ 3:01 PM
Study NCT ID:
NCT05905406
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-06-15
First Post:
2023-05-23
Brief Title:
Effect of Femoral Quadriceps Muscle Length on Fatigue Induced by Neuromuscular Electrical Stimulation
Sponsor:
University of Brasilia
Organization:
University of Brasilia
Study Overview
Official Title:
Effect of Femoral Quadriceps Muscle Length on Fatigue Neuromuscular Performance Oxygen Uptake and Discomfort Induced by Neuromuscular Electrical Stimulation
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims To investigate the effects of Quadriceps femoris muscle length on neuromuscular fatigue induced by NMES muscle performance discomfort and peripheral oxygen extraction
Detailed Description:
This is a crossover experimental randomized and double-blind trial participant and statistician The procedures will be performed at the Neuromuscular Performance Laboratory and the Musculotendineal Plasticity Laboratory LaPlasT of the Faculty of CeilândiaUniversity of Brasília to evaluate the neuromuscular fatigue generated during NMES of the QF muscle in different muscle lengths according to the articular angles of the hip and knee Participants aged between 18 and 45 years of age of both sexes healthy with body mass index BMI between 185 and 249 kg m² ie eutrophic who did not perform systematic training to strengthen the lower limbs in the last six months practitioners or not of recreational sports activities physically active according to the International Physical Activity Questionnaire IPAQ and with minimum torque reach of 20 of MVC during NMES without excessive discomfort Those who have edema dermal injury limitation of the range of joint motion deformity or amputation in any part of the lower limbs as well as a history of patellar dislocation or trauma to the lower limbs or trunk that compromises the results Also excluded are those with conditions that affect musculotendineal morphology or neuromuscular excitability such as diabetes mellitus type II familial hypercholesterolemia neuromuscular disease and severe cardiopathy or conditions that procedures such as cognitive impairment psychiatric disease chemical dependence or behavioral problems Dudley-Javoroski et al 2010 Participants will be initially familiar with assessments and training with EENM In familiarization will be performed Antropometry height and body mass location of the motor points randomization of the order of articular positioning that will be evaluated muscle enhancement and three CVIM The fatigue protocol with NMES will occur at 20 of MVC in positions bench press with knee at 60º of flexion Sup60 sitting with knee at 60º Sen60 bench press at 20º Sup20 and Sitting with knee at 20º Sen20 These positions were chosen considering that 1 SJ60 is the position in which the knee angle provides the optimal QF length for maximum torque production Scott et al 2019 and the hip angle provides a neutral length for the RF Bampouras et al 2017 2 QF is commonly stimulated with knees fully extended Fitzgerald et al 2003 However with the knees extended it is not possible to measure the extensor torque of the knee properly in the isokinetic dynamometer Babault et al 2003 Therefore we chose 20º knee flexion as an approximate position 3 the hip angle affects the length of RF and myotendinous stiffness of QF Bampouras et al 2017 so the knee angles 60º and 20º will be evaluated with the participants both seated hip in flexion 85º when lying down hip in extension 0º During familiarization for anthropometric assessment height body mass and BMI participants will be barefoot and wearing light clothes The BMI will be obtained by the ratio of the weight of the participants in kilos with the square of the height kgm2 To determine the level of engagement in physical activities the IPAQ will be applied which contains 7 items that assess the frequency days and duration minutes and or hours spent on physical activities in the last week Scholes et al 2016 After familiarization there will be four sessions of fatigue induced by NMES composed of 20 electrically induced contractions at 20 of CVM CEI20 Each session will be as confirmed by the volunteer regarding the absence of any residual muscle discomfort arising from the previous session The sessions will be initiated with heating and muscle enhancement The following outcomes will be observed before during and after the fatigue protocol CVIM reflex H Wave M and voluntary activation level electromyographic activity muscular architecture tendinous properties and tissue oxygen extraction During the fatigue protocol five first and five last evoked contractions will be evaluated 1 fatigability by the torque decay curve 2 integral force-time 3 tissue extraction of oxygen
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None