Ignite Creation Date:
2024-05-06 @ 7:07 PM
Last Modification Date:
2024-10-26 @ 3:01 PM
Study NCT ID:
NCT05908838
Status:
COMPLETED
Last Update Posted:
2023-06-18
First Post:
2023-06-08
Brief Title:
Clinical Study of Modified Banxia Xiexin Decoction Treatment on Gastric Cancer
Sponsor:
ShuGuang Hospital
Organization:
ShuGuang Hospital
Study Overview
Official Title:
Randomized Clinical TrialClinical Study of Modified Banxia Xiexin Decoction Treatment on Gastric Cancer
Status:
COMPLETED
Status Verified Date:
2023-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Research purpose To elucidate the effect mechanism and clinical effective of Modified Banxia Xiexin Decoction in the prevention and treatment of gastric cancer From genes related to cell differentiation proliferation apoptosis tumor invasion and metastasis genes related to immune inflammation and immune escape and other possible aspects to elucidate the effective and mechanism of Modified Banxia Xiexin Decoctions treatment on gastric cancer
Detailed Description:
Modified Banxia Xiexin Decoction treatment and mechanism on Gastric Cancer Main Responsibility Person Mingyu Sun research centerShuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Trial ObjectiveObserve the clinical efficacy and mechanism of Modified Banxia Xiexin Decoction in the treatment gastric cancer Therapeutic ScheduleIn this study 146patients with gastric cancer who received chemotherapy in the Department of Gastrointestinal Surgery and Oncology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine were recruited and divided into groups according to random number table method namely 73 patients in the Modified Banxia Xiexin Decoction combined chemotherapy group and 73 patients in the Placebo granules combined chemotherapy groupModified Banxia Xiexin Decoction group was treated with 18 weeks of Chinese patent medicine Modified Banxia Xiexin Decoction at the same time of chemotherapy The Overall survival Progression-free survival Solid tumor efficacy TCM syndrome score quality of life score Tumor markers Immune function and adverse reactions of the two groups before and 18 weeks after treatment were observed and compared Elucidate the possible mechanism of action of Modified Banxia Xiexin Decoction in the treatment of gastric cancer patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None