Ignite Creation Date:
2024-05-06 @ 7:06 PM
Last Modification Date:
2024-10-26 @ 3:00 PM
Study NCT ID:
NCT05892003
Status:
RECRUITING
Last Update Posted:
2023-11-01
First Post:
2023-05-17
Brief Title:
Scot Sweet Study Interaction of a Non-nutritive Sweetener With a High-fibre Weight Loss Diet
Sponsor:
University of Aberdeen
Organization:
University of Aberdeen
Study Overview
Official Title:
Healthy Diets for a Healthy Weight Exploring Physiological Mechanisms Related to Dietary Fibre and Non-Nutritive Sweeteners
Status:
RECRUITING
Status Verified Date:
2023-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SSS
Brief Summary:
The investigators present a weight loss diet intervention study to be conducted as a within-subject design with all food and beverages provided to assess interaction of non-nutritive sweetener sucralose with a high-fibre weight loss diet on markers of gut health in humans This study will allow assessment of the effects of a non-nutritive sweetener sucralose with a high-fibre soluble fibre fructo-oligosaccharides FOS diet on metabolic health and activity and composition of gut microbiota by a controlled human diet intervention study The investigators propose to recruit participants living with obesity with a poor diet quality moderate habitual fibre intake to additionally address diet inequalities in the research approach and this will also allow examine the time-course of adaptation of the gut microbiome measured in faecal samples The investigators will also assess changes in free-living glycaemic control with addition of dietary fibre and bio-markers of health
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None