Ignite Creation Date:
2024-05-06 @ 7:06 PM
Last Modification Date:
2024-10-26 @ 3:00 PM
Study NCT ID:
NCT05892731
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2023-06-07
First Post:
2023-05-25
Brief Title:
Study of Cognitive Reserve Disorder Affecting Depression in Aged Related Hearing Loss Via Rest State EEG
Sponsor:
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Organization:
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Study Overview
Official Title:
Study of Cognitive Reserve Disorder Affecting Depression in Age- Related Hearing Loss Via Rest State EEG
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2023-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study patients with aged-related hearing loss with depression and without depression were evaluated by audiometry pure tone audiometry and speech audiometry cognitive function assessment MMSE scale for simple mental state test MoCA Scale for Montreal Cognitive Assessment and depressive symptoms assessment GDS-15 and HAMD resting state EEG The ananlysis of resting state EEG included power spectral density traceability analysis functional connectivity microstate clustering coefficient characteristic path length characteristic path permeability and compatibility coefficient EEG signals were used to explore the activation of brain regions and poor connectivity of brain regions affected by cognitive reserve dissonance on the level of brain imaging This paper innovatively explores the influence of cognitive reserve dissonance on depressive mood in senile deafness by means of audiological assessment cognitive function assessment depression symptom assessment resting state electroencephalography EEG and other technical means Auditory and cognitive cortical activation functional connectivity of brain regions small-world attributes and microstates were analyzed in senile deafness with or without depression at the brain imaging level
Detailed Description:
In this study patients with aged-related hearing loss with depression and without depression were evaluated by audiometry pure tone audiometry and speech audiometry cognitive function assessment MMSE scale for simple mental state test MoCA Scale for Montreal Cognitive Assessment and depressive symptoms assessment GDS-15 and HAMD resting state EEG The ananlysis of resting state EEG included power spectral density traceability analysis functional connectivity microstate clustering coefficient characteristic path length characteristic path permeability and compatibility coefficient EEG signals were used to explore the activation of brain regions and poor connectivity of brain regions affected by cognitive reserve dissonance on the level of brain imaging This paper innovatively explores the influence of cognitive reserve dissonance on depressive mood in senile deafness by means of audiological assessment cognitive function assessment depression symptom assessment resting state electroencephalography EEG and other technical means Auditory and cognitive cortical activation functional connectivity of brain regions small-world attributes and microstates were analyzed in senile deafness with or without depression at the brain imaging level
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None