Ignite Creation Date:
2024-05-06 @ 7:06 PM
Last Modification Date:
2024-10-26 @ 3:00 PM
Study NCT ID:
NCT05892224
Status:
RECRUITING
Last Update Posted:
2023-06-07
First Post:
2023-03-10
Brief Title:
Study on Brain Function of Obesity Classification
Sponsor:
Shanghai 10th Peoples Hospital
Organization:
Shanghai 10th Peoples Hospital
Study Overview
Official Title:
Research on Brain Function of Metabolism-based Artificial Intelligence Assisted Clinical Classification of Obesity
Status:
RECRUITING
Status Verified Date:
2023-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study was to investigate the differences and similarities of brain function in patients with four subtypes of obesity and the relationship between brain function changes and complications after weight loss and metabolic improvement 120 patients with obesity and 30 healthy individuals with normal BMI were enrolled
Detailed Description:
Although the investigators have clinically observed significant differences in appetite and metabolic status in patients with the above four types of obesity the brain functional characteristics of different obesity subtypes and their relationship with metabolic markers are still unclear Based on this in this project the investigators plan to explore further the similarities and differences in brain function in patients with four subtypes of obesity and the relationship between brain function changes after weight loss and metabolic improvement and the occurrence of complications
120 patients with obesity and 30 healthy individuals with normal BMI were enrolled
All patients with obesity underwent LSG A multidisciplinary team evaluated participants with obesity at baseline 1 3 6 and 12 months after laparoscopic sleeve gastrectomy LSG Anthropometrics Metabolic indicators sex hormones menstruationglucose-lipid metabolic markers and hepatic steatosis assessed by FibroScanCAP value and E value were measured baseline and postoperative Resting and task state functional magnetic resonance imaging fMRI measurements were performed at baseline for all participants at two-time points before and after meals Measurements were repeated in obese patients 6 months after surgery
120 patients with obesity and 30 healthy individuals with normal BMI were enrolled
All patients with obesity underwent LSG A multidisciplinary team evaluated participants with obesity at baseline 1 3 6 and 12 months after laparoscopic sleeve gastrectomy LSG Anthropometrics Metabolic indicators sex hormones menstruationglucose-lipid metabolic markers and hepatic steatosis assessed by FibroScanCAP value and E value were measured baseline and postoperative Resting and task state functional magnetic resonance imaging fMRI measurements were performed at baseline for all participants at two-time points before and after meals Measurements were repeated in obese patients 6 months after surgery
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None