Ignite Creation Date:
2024-05-06 @ 7:03 PM
Last Modification Date:
2024-10-26 @ 2:59 PM
Study NCT ID:
NCT05876468
Status:
RECRUITING
Last Update Posted:
2023-05-25
First Post:
2022-08-08
Brief Title:
Effects of Continuous Anterior Chest Compression
Sponsor:
Assistance Publique - Hôpitaux de Paris
Organization:
Assistance Publique - Hôpitaux de Paris
Study Overview
Official Title:
Effects of Continuous Anterior Chest Compression CACC Comparision With Prone Position in ARDS Patients The StrapVent Study
Status:
RECRUITING
Status Verified Date:
2023-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
StrapVent
Brief Summary:
The aim is to test the physiological effects of continuous anterior chest compression in patients with severe to moderate ARDS
Detailed Description:
Acute respiratory distress syndrome ARDS is usually characterized by inhomogeneous lesions leading to an inhomogeneous distribution of the mechanical ventilation with the following several deleterious effects atelectrauma of dependent posterior areas and overdistension in the anterior ones Therefore the gold standard treatment is to prevent VILI with lung protective ventilation low tidal volume high positive end expiratory pressure and prone positioning which is a technique that reduces mortality Prone positioning has several beneficial effects it relieves cardiac compression of the supporting lung it stiffens the anterior chest wall thus limiting the risk of overdistension of anterior areas and promotes recruitment of non-dependent posterior pulmonary units The overall effect is a more uniform distribution of transpulmonary pressures and improved ventilation to perfusion ratios
Similar to prone positioning continuous anterior chest wall compression stiffens the anterior chest wall The investigators hypothesize that such reduction in anterior chest wall compliance may protect against overdistension and promote the redistribution of the ventilation in posterior areas
Similar to prone positioning continuous anterior chest wall compression stiffens the anterior chest wall The investigators hypothesize that such reduction in anterior chest wall compliance may protect against overdistension and promote the redistribution of the ventilation in posterior areas
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None