Ignite Creation Date:
2024-05-06 @ 7:03 PM
Last Modification Date:
2024-10-26 @ 2:59 PM
Study NCT ID:
NCT05875662
Status:
COMPLETED
Last Update Posted:
2024-04-26
First Post:
2023-05-07
Brief Title:
Pulmonary Ventilation After Fiberoptic Bronchoscopy Using EIT
Sponsor:
Peking University Peoples Hospital
Organization:
Peking University Peoples Hospital
Study Overview
Official Title:
Evaluation of Pulmonary Ventilation After Fiberoptic Bronchoscopy in Critically Ill Patients Using Electrical Impedance Tomography
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background Fiber bronchoscopy is a routine operation in intensive care unit ICU but it may cause local collapse of the lung Recruitment maneuver RM after fiber bronchoscopy may have the potential to restore functional residual air volume and increase lung volume However there is still a lack of quantitative indicators to evaluate the effect of recruitment maneuver With electrical impedance tomography EIT we can monitor lung ventilation in real time to understand the situation of lung ventilation
Objective To evaluate whether recruitment maneuver after fiber bronchoscopy can improve lung volume and improve lung ventilation and which people are most likely to benefit from it by monitoring the end expiratory pulmonary impedance of critically ill patients undergoing bedside fiber bronchoscopy to monitor the lung ventilation before and after the operation and before and after recruitment maneuver
Study Design A prospective observational study was conducted to monitor the end expiratory lung impedance EELI tidal impedance variable TIV global inhomogeneity GI index and Center of Ventilation CoV before and after bronchoscopy and recruitment maneuver and then to understand the changes of lung volume and ventilation
Objective To evaluate whether recruitment maneuver after fiber bronchoscopy can improve lung volume and improve lung ventilation and which people are most likely to benefit from it by monitoring the end expiratory pulmonary impedance of critically ill patients undergoing bedside fiber bronchoscopy to monitor the lung ventilation before and after the operation and before and after recruitment maneuver
Study Design A prospective observational study was conducted to monitor the end expiratory lung impedance EELI tidal impedance variable TIV global inhomogeneity GI index and Center of Ventilation CoV before and after bronchoscopy and recruitment maneuver and then to understand the changes of lung volume and ventilation
Detailed Description:
At present people pay more and more attention to the atelectasis caused by the sputum suction operation of fiberoptic bronchoscope A recent observational study confirmed that more than 80 of patients will have atelectasis in at least one lung segment after the completion of the bronchoscope operation using the imaging method of cluster computed tomography CT The production of atelectasis will affect the patients subsequent ventilation function causing hypoxemia Pulmonary atelectasis is a commonly used procedure for patients with acute respiratory distress syndrome ARDS to restore lung volume and improve atelectasis Therefore it is worth exploring whether adopting recruitment maneuver after bronchoscopy can avoid or reduce the problems of subsequent lung collapse and atelectasis in patients and how to quantify it
electrical impedance tomography referred to as EIT is a new imaging technology that can be implemented at the bedside in real-time non-invasive and radiation free The basic principle is to apply a weak current through local electrodes to sense the changes in the chest bioelectrical impedance during breathing and then use the corresponding imaging algorithm to monitor the status of ventilation function in different areas of the lung which is presented in real-time dynamic lung tomography ventilation images Previous studies have found that through EIT the end expiratory lung impedance EELI of the lungs can be monitored indirectly reflecting the end expiratory volume of the lungs thereby achieving the goal of monitoring local lung collapse caused by fiberoptic bronchoscope
After being included in the patient the EIT chest strap was worn to measure the end expiratory lung impedance and tidal impedance variable before bronchoscopy and recorded as EELI before and TIV before global inhomogeneity GI index Center of Ventilation CoV the vital signs of patients including heart rate blood pressure respiratory rate SpO2 ventilator parameters including mode PCVt FiO2 PEEP and lung compliance before bronchoscopy were recorded Prepare fiber bronchoscopy and perform fiber bronchoscopy according to routine procedures in ICU Record the duration of fiberoptic bronchoscopy examination and the condition of secretions
After the fiber bronchoscopy examination the end expiratory lung impedance and tidal impedance variables were recorded as EELI after operation and TIV after operation The GI index CoV vital signs of patients including heart rate blood pressure respiratory rate SpO2 ventilator parameters including mode PCVt FiO2 PEEP and compliance were recorded Perform recruitment maneuver using PCV mode PEEP 20 cmH2O PC 20 cmH2O for 1 minute then gradually reduce the ventilator pressure and restore the mode and parameters before bronchoscopy If complications occur during the process of recruitment maneuver timely record them End expiratory lung impedance and tidal impedance variables were recorded as EELI after recruitment and TIV after recruitment The GI index CoV vital signs of patients including heart rate blood pressure respiratory rate SpO2 ventilator parameters including mode PCVt FiO2 PEEP and compliance were recorded
electrical impedance tomography referred to as EIT is a new imaging technology that can be implemented at the bedside in real-time non-invasive and radiation free The basic principle is to apply a weak current through local electrodes to sense the changes in the chest bioelectrical impedance during breathing and then use the corresponding imaging algorithm to monitor the status of ventilation function in different areas of the lung which is presented in real-time dynamic lung tomography ventilation images Previous studies have found that through EIT the end expiratory lung impedance EELI of the lungs can be monitored indirectly reflecting the end expiratory volume of the lungs thereby achieving the goal of monitoring local lung collapse caused by fiberoptic bronchoscope
After being included in the patient the EIT chest strap was worn to measure the end expiratory lung impedance and tidal impedance variable before bronchoscopy and recorded as EELI before and TIV before global inhomogeneity GI index Center of Ventilation CoV the vital signs of patients including heart rate blood pressure respiratory rate SpO2 ventilator parameters including mode PCVt FiO2 PEEP and lung compliance before bronchoscopy were recorded Prepare fiber bronchoscopy and perform fiber bronchoscopy according to routine procedures in ICU Record the duration of fiberoptic bronchoscopy examination and the condition of secretions
After the fiber bronchoscopy examination the end expiratory lung impedance and tidal impedance variables were recorded as EELI after operation and TIV after operation The GI index CoV vital signs of patients including heart rate blood pressure respiratory rate SpO2 ventilator parameters including mode PCVt FiO2 PEEP and compliance were recorded Perform recruitment maneuver using PCV mode PEEP 20 cmH2O PC 20 cmH2O for 1 minute then gradually reduce the ventilator pressure and restore the mode and parameters before bronchoscopy If complications occur during the process of recruitment maneuver timely record them End expiratory lung impedance and tidal impedance variables were recorded as EELI after recruitment and TIV after recruitment The GI index CoV vital signs of patients including heart rate blood pressure respiratory rate SpO2 ventilator parameters including mode PCVt FiO2 PEEP and compliance were recorded
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None