Ignite Creation Date:
2024-05-06 @ 7:02 PM
Last Modification Date:
2024-10-26 @ 2:59 PM
Study NCT ID:
NCT05874999
Status:
COMPLETED
Last Update Posted:
2023-06-07
First Post:
2023-03-30
Brief Title:
Acute Effects of Supramaximal High-Intensity Interval Training in People With COPD
Sponsor:
Umeå University
Organization:
Umeå University
Study Overview
Official Title:
Feasibility and Acute Effects of Supramaximal High-Intensity Interval Training in People With COPD
Status:
COMPLETED
Status Verified Date:
2023-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
COPD-HIIT-AC
Brief Summary:
High-intensity exercise is essential for optimal development of cardiorespiratory fitness and health This is however challenging for most people with chronic obstructive pulmonary disease COPD due to ventilatory limitations leading to exercise at lower intensities accompanied by suboptimal stress on the cardiovascular and muscular system
The aims of this cross-over trial is
1 To compare the acute effects of short-duration supramaximal high-intensity interval training HIIT vs traditional moderate-intensity continuous training MICT in people with COPD and matched healthy controls HC
2 To investigate the feasibility of supramaximal HIIT in people with COPD and matched HC
3 To compare the cardiorespiratory demand exercise intensity and symptoms during a modified Borg Cycle Strength Test BCST and a cardiopulmonary exercise test CPET in people with COPD and HC
The aims of this cross-over trial is
1 To compare the acute effects of short-duration supramaximal high-intensity interval training HIIT vs traditional moderate-intensity continuous training MICT in people with COPD and matched healthy controls HC
2 To investigate the feasibility of supramaximal HIIT in people with COPD and matched HC
3 To compare the cardiorespiratory demand exercise intensity and symptoms during a modified Borg Cycle Strength Test BCST and a cardiopulmonary exercise test CPET in people with COPD and HC
Detailed Description:
In this study eligible participants attended the facility four times within 14 days with at least 48 hours of rest between visits
Exercise tests visit 1 week 1
After pulmonary functions tests a CPET on a stationary bicycle was performed according to international guidelines After 15 hours of recovery a BCST was performed to assess anaerobic exercise capacity and determine exercise intensities for supramaximal HIIT
Exercise sessions visit 2 - week 1 visit 3 - week 2 visit 4 - week 2
The order of the two first exercise sessions HIIT at 60 of MPO6 or MICT on a stationary bicycle were randomized The exercise session at HIIT at 80 of MPO6 was always the third exercise session
During all exercise sessions blood collection was performed at baseline after a 15-minute seated rest During HIIT blood was collected immediately after and 30 minutes after the 10-minute HIIT period For MICT blood was collected after 10 minutes isotime in relation to HIIT immediately after and 30 minutes of cycling at 60 MAP
Exercise tests visit 1 week 1
After pulmonary functions tests a CPET on a stationary bicycle was performed according to international guidelines After 15 hours of recovery a BCST was performed to assess anaerobic exercise capacity and determine exercise intensities for supramaximal HIIT
Exercise sessions visit 2 - week 1 visit 3 - week 2 visit 4 - week 2
The order of the two first exercise sessions HIIT at 60 of MPO6 or MICT on a stationary bicycle were randomized The exercise session at HIIT at 80 of MPO6 was always the third exercise session
During all exercise sessions blood collection was performed at baseline after a 15-minute seated rest During HIIT blood was collected immediately after and 30 minutes after the 10-minute HIIT period For MICT blood was collected after 10 minutes isotime in relation to HIIT immediately after and 30 minutes of cycling at 60 MAP
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None