Ignite Creation Date:
2024-05-06 @ 7:02 PM
Last Modification Date:
2024-10-26 @ 2:59 PM
Study NCT ID:
NCT05870033
Status:
COMPLETED
Last Update Posted:
2023-12-01
First Post:
2023-05-02
Brief Title:
Muscle Activation in Knee Osteoarthritis
Sponsor:
University of Pecs
Organization:
University of Pecs
Study Overview
Official Title:
Gender Difference of Muscle Activation Amongst Patients With Knee Osteoarthritis
Status:
COMPLETED
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Muscle activity as a possible fundamental cause of functional limitation has been extensively investigated in knee osteoarthritis KOA Many trials investigated muscle activity during dynamic movements and functional tasks in KOA In addition gender-related differences has been also investigated during functional movements in KOA However no trial investigated gender-related differences in muscle activation during static movement in KOA
Detailed Description:
Muscle activity as a possible fundamental cause of functional limitation has been extensively investigated in knee osteoarthritis KOA Interestingly studies concentrated mainly on investigation of muscle activity during dynamic movements and different functional tests Moznuzzaman et al displayed greater muscle activation during sitting to standing test STS and standing to sitting test in KOA patients compared to healthy participants Interestingly some studies investigated muscle activation standing up from a knee-height seat during STS and illustrated a greater muscle activation amongst KOA patients compared to healthy controls Moreover Amer et al found greater muscle activation while performing STS from a lower height seat compared to a knee-height seat amongst women and men patients with unibilateral KOA These findings might be of interest due to compensatory mechanisms observed by female patients during STS transition increases loading on the joint surfaces and consequently leading to progression of KOA Furthermore different studies also presented gender-differences of muscle activation during different weight-bearing tasks gait STS stair ascenddescend and squat amongst patients with KOA and healthy control Interestingly both studies showed women with KOA representing higher muscle activation compared to men Therefore an analytical comparative study might be useful for identification of gender-differences in muscle activation amongst patients with KOA
Investigation of static muscle activity during functional movements is very rare in KOA Zhang et al investigated muscle activation after single whole body vibration trial in standing position at 0 30 and 60 static knee flexion angles amongst women with KOA Authors found that muscle activation in 60 was greater compared to 30 and it was also greater in 30 compared to 0 Based on our literature search no further study examined muscle activity in static knee flexion in KOA However investigating static knee flexion might be useful as it could be related to different knee moments in KOA
Investigation of static muscle activity during functional movements is very rare in KOA Zhang et al investigated muscle activation after single whole body vibration trial in standing position at 0 30 and 60 static knee flexion angles amongst women with KOA Authors found that muscle activation in 60 was greater compared to 30 and it was also greater in 30 compared to 0 Based on our literature search no further study examined muscle activity in static knee flexion in KOA However investigating static knee flexion might be useful as it could be related to different knee moments in KOA
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None