Ignite Creation Date:
2024-05-06 @ 7:00 PM
Last Modification Date:
2024-10-26 @ 2:59 PM
Study NCT ID:
NCT05869474
Status:
RECRUITING
Last Update Posted:
2023-08-04
First Post:
2023-05-11
Brief Title:
Implantation of iodine125-Seeds Combined With Chemotherapy in the Treatment of Metastatic Pancreatic Carcinoma
Sponsor:
Changhai Hospital
Organization:
Changhai Hospital
Study Overview
Official Title:
Endoscopic Ultrasound-guided Intratumoral Iodine125-Seeds Implantation Combined With GemNab-P Chemotherapy Versus GemNab-P Alone for Metastatic Pancreatic Carcinoma a Randomized Controlled Trial
Status:
RECRUITING
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to evaluate the clinical efficacy and safety of endoscopic ultrasonography EUS-guided radioactive iodine 125 seeds in combination with AG regimen chemotherapy for the treatment of metastatic pancreatic cancer The main questions it aims to answer are
whether the combination of minimally invasive endoscopy-guided local radiation therapy with chemotherapy may improve overall survival
the adverse events of the combination therapy Participants will receive the implantation of radioactive seeds under EUS guide 48h after implantation chemotherapy with Gemnab-P given on days 1 and 8 of each 21-day cycle will be conducted
Researchers will compare the I125AG group with the group that takes AG chemotherapy alone to see if the overall survival can be improved
whether the combination of minimally invasive endoscopy-guided local radiation therapy with chemotherapy may improve overall survival
the adverse events of the combination therapy Participants will receive the implantation of radioactive seeds under EUS guide 48h after implantation chemotherapy with Gemnab-P given on days 1 and 8 of each 21-day cycle will be conducted
Researchers will compare the I125AG group with the group that takes AG chemotherapy alone to see if the overall survival can be improved
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None