Viewing Study NCT05850117



Ignite Creation Date: 2024-05-06 @ 6:59 PM
Last Modification Date: 2024-10-26 @ 2:58 PM
Study NCT ID: NCT05850117
Status: RECRUITING
Last Update Posted: 2023-05-09
First Post: 2023-04-28

Brief Title: Efficacies of Tetracycline-levofloxacin Standard Bismuth Amoxicillin-levofloxacin Quadruple Therapy for Hp
Sponsor: Kaohsiung Medical University
Organization: Kaohsiung Medical University

Study Overview

Official Title: Efficacies of Tetracycline-levofloxacin Quadruple Therapy Standard Bismuth Quadruple Therapy and Amoxicillin-levofloxacin Quadruple Therapy in the Second-line Treatment of H Pylori Infection
Status: RECRUITING
Status Verified Date: 2023-04
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: 1 Compare the efficacy of Tetracycline combined with levofloxacin quadruple therapy standard tincture quadruple therapy and amoxicillin combined with levofloxacin quadruple therapy on the second line of Helicobacter pylori sterilization
2 To investigate the drug resistance of Helicobacter pylori and the host genotypes of CYP2C19 and IL-1B-511 on the sterilizing effect of three second-line Helicobacter pylori
Detailed Description: The standard tincture quadruple therapy and the proton pump inhibitor combined with fluoroquinolone and amoxicillin triple therapy recommended by the 5th Mazdock-Florence Consensus Conference on the second line of Helicobacter pylori treatment The sterilization rate is not ideal less than 80 Recently we have developed a Tetracycline combined with levofloxacin quadruple therapy for first-line treatment failure of H pylori infection with a relatively high sterilization rate 95 A randomized controlled trial confirmed that the elimination rate of Tetracycline combined with levofloxacin quadruple therapy was better than proton pump inhibitor combined with fluoroquinolone after standard triple therapy and non-tank tetratherapy sterilization failure Triple therapy with amoxicillin

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None