Ignite Creation Date:
2024-05-06 @ 6:57 PM
Last Modification Date:
2024-10-26 @ 2:58 PM
Study NCT ID:
NCT05847491
Status:
RECRUITING
Last Update Posted:
2023-05-06
First Post:
2023-04-27
Brief Title:
Latent Tuberculosis in Healthcare Workers - the Reality of a Portuguese Tertiary Hospital
Sponsor:
Centro Hospitalar do Oeste
Organization:
Centro Hospitalar do Oeste
Study Overview
Official Title:
Latent Tuberculosis in Healthcare Workers - the Reality of a Portuguese Tertiary Hospital
Status:
RECRUITING
Status Verified Date:
2023-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Prospective descriptive study to assess latent tuberculosis infection LTBI among healthcare worker HCW in a tertiary hospital in a low-risk area
Detailed Description:
identification and treatment of LTBI can substantially reduce the risk of development of disease and are important TB control strategies especially in settings with a low tuberculosis TB incidence where reactivation of LTBI often accounts for the majority of non-imported TB disease treatment of LTBI can substantially reduce the risk of development of disease
In Portugal the real prevalence of LTBI in low-risk HCWs has not been evaluated since they are not included in the periodic screening programs It is important to diagnose TB infections in HCWs to prevent nosocomial transmission particularly among immunocompromised patients
The risk for transmission varies by setting occupational group local prevalence of TB patient population and effectiveness of TB infection control measures
Prevention of active TB disease by treatment of LTBI is a critical component for public health
Tuberculin skin test TST is used worldwide to diagnose LTBI whereas interferon-γ release assay IGRA are used in some countries according to their national TB programs IGRA offers a potential method of serial testing to diagnose LTBI in HCWs and it has better specificity than that of TST in one-time screening
Study participants should be identified and contacted by occupational health service In association study information should be disseminated through posters and institutional email
In Portugal the real prevalence of LTBI in low-risk HCWs has not been evaluated since they are not included in the periodic screening programs It is important to diagnose TB infections in HCWs to prevent nosocomial transmission particularly among immunocompromised patients
The risk for transmission varies by setting occupational group local prevalence of TB patient population and effectiveness of TB infection control measures
Prevention of active TB disease by treatment of LTBI is a critical component for public health
Tuberculin skin test TST is used worldwide to diagnose LTBI whereas interferon-γ release assay IGRA are used in some countries according to their national TB programs IGRA offers a potential method of serial testing to diagnose LTBI in HCWs and it has better specificity than that of TST in one-time screening
Study participants should be identified and contacted by occupational health service In association study information should be disseminated through posters and institutional email
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None