Ignite Creation Date:
2024-05-06 @ 6:56 PM
Last Modification Date:
2024-10-26 @ 2:57 PM
Study NCT ID:
NCT05837325
Status:
RECRUITING
Last Update Posted:
2024-02-07
First Post:
2023-03-13
Brief Title:
Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst
Sponsor:
ART Fertility Clinics LLC
Organization:
ART Fertility Clinics LLC
Study Overview
Official Title:
Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst A Prospective Study
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To investigate whether on the day of egg retrieval after ovarian stimulation for ICSI intracytoplasmic sperm injection there is a correlation between the intrafollicular AMH Anti-Müllerian hormone levels and the ploidy status of the blastocyst
Detailed Description:
In clinical practice AMH is used as a diagnostic andor prognostic marker in women in association with ovulation induction and in various pathophysiological conditions This study looks to investigate if the hormonal environment that surrounds an oocyte has an impact on the ploidy status of the blastocyst Nowadays using NGS Next Generation Sequencing platform for analysis of 23 pairs of chromosomes for Preimplantation Genetic Testing on blastocysts the ploidy status of the embryo is more adequately assessed Furthermore embryo culture to blastocyst will provide further information about embryo quality and possibilities of implantation
To have complete information between the serum hormones follicular hormones embryo development and ploidy will provide to clinicians embryologist and patients further information on embryo selection and adequate ovarian stimulation protocols
The database will be exported from the clinical information manager VRepro to a table in excel format through a database-based query system The exported data will be duly codified to protect the clinical and personal information of the participants Prior to the statistical study an exploratory data analysis will be carried out to review the quality of the information extracted
To have complete information between the serum hormones follicular hormones embryo development and ploidy will provide to clinicians embryologist and patients further information on embryo selection and adequate ovarian stimulation protocols
The database will be exported from the clinical information manager VRepro to a table in excel format through a database-based query system The exported data will be duly codified to protect the clinical and personal information of the participants Prior to the statistical study an exploratory data analysis will be carried out to review the quality of the information extracted
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None