Ignite Creation Date:
2024-05-06 @ 6:55 PM
Last Modification Date:
2024-10-26 @ 2:57 PM
Study NCT ID:
NCT05833529
Status:
RECRUITING
Last Update Posted:
2024-06-10
First Post:
2023-03-27
Brief Title:
Innovative Cognitive and Behavioral Psychotherapy for Cocaine Use Disorder
Sponsor:
Thomas Lehoux
Organization:
University Hospital Center of Martinique
Study Overview
Official Title:
Virtual Reality Cue Exposure Therapy for Cocaine Craving an Innovative Cognitive and Behavioral Psychotherapy for Cocaine Use Disorder Psychothérapie Innovante COmportementale et Cognitive Pour le Trouble dUsage de Cocaïne PICOC
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PICOC
Brief Summary:
Cocaine is the 2nd most used illicit substance in Europe and its use implies numerous health complications as well as an annual social cost of 87 G d Classical picture video audio imagery based or in vivo cue exposure therapy for substance craving CET ie the irrepressible and non-voluntary desire to use the substance failed to prove efficacious in treating substance use disorder Virtual reality cue exposure therapy for substance craving VRCET is more immersive realistic and controllable and is suggested as being a more efficacious intervention in reducing craving as compared to classical CET
So far its still not known thus the secondary aim of the present randomized and clinical trial is to investigate whether virtual reality cue exposure is more efficacious as compared to classical cue exposure in both eliciting and reducing cocaine craving in a clinical context of CET for cocaine craving The main study aim to is to investigate whether a VRCET for cocaine craving based cognitivo-behavioral therapy ie VRCET followed by memory focused cognitive therapy is more efficacious than a behavioural therapy ie classical exposure therapy to craving in reducing cocaine craving
To do so 54 voluntary residential patients in treatment for cocaine use disorder will be recruited from the Universitary Hospital Center of Martinique CHUM Martinique France and Saint-Esprit Hospital Center CHSE Martinique France and randomly allocated in either a 3 weeks individual experimental treatment 10 meetings of VRET for cocaine craving followed by 5 meetings of memory focused cognitive therapy or a 3 weeks individual control treatment 15 meetings of pictures based exposure therapy for cocaine craving Self-reported measures of retrospective last 14 days and in virtuo exposure cocaine craving will be collected at the beginning after 10 days after 15 days of treatment and 1 month post Others secondary subjective urinary and physiological cocaine use related measures will also be collected
So far its still not known thus the secondary aim of the present randomized and clinical trial is to investigate whether virtual reality cue exposure is more efficacious as compared to classical cue exposure in both eliciting and reducing cocaine craving in a clinical context of CET for cocaine craving The main study aim to is to investigate whether a VRCET for cocaine craving based cognitivo-behavioral therapy ie VRCET followed by memory focused cognitive therapy is more efficacious than a behavioural therapy ie classical exposure therapy to craving in reducing cocaine craving
To do so 54 voluntary residential patients in treatment for cocaine use disorder will be recruited from the Universitary Hospital Center of Martinique CHUM Martinique France and Saint-Esprit Hospital Center CHSE Martinique France and randomly allocated in either a 3 weeks individual experimental treatment 10 meetings of VRET for cocaine craving followed by 5 meetings of memory focused cognitive therapy or a 3 weeks individual control treatment 15 meetings of pictures based exposure therapy for cocaine craving Self-reported measures of retrospective last 14 days and in virtuo exposure cocaine craving will be collected at the beginning after 10 days after 15 days of treatment and 1 month post Others secondary subjective urinary and physiological cocaine use related measures will also be collected
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2022-A02440-43 | REGISTRY | ID-RCB | None |