Ignite Creation Date:
2024-05-06 @ 6:55 PM
Last Modification Date:
2024-10-26 @ 2:57 PM
Study NCT ID:
NCT05829785
Status:
COMPLETED
Last Update Posted:
2023-10-17
First Post:
2023-04-13
Brief Title:
Influence of Obesity on Microvascular Reactivity During General Anesthesia
Sponsor:
Pusan National University Hospital
Organization:
Pusan National University Hospital
Study Overview
Official Title:
Influence of Obesity on Microvascular Reactivity During General Anesthesia
Status:
COMPLETED
Status Verified Date:
2023-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study was to investigate the effect of obesity on changes in microvascular reactivity and tissue oxygen saturation StO2 during general anesthesia using near-infrared spectroscopy in conjunction with vascular occlusion tests VOT
For this prospective observation investigation a total of 128 patients who underwent elective surgery under general anesthesia at Pusan National University Hospital between June 2018 and February 2021 were participated in this study Baseline StO2 on thenar eminence hemodynamics and laboratory profile were monitored before Tpre and 30 min after general anesthesia Tpost During vascular occlusion tests VOT the occlusion slope representing oxygen consumption of muscle and recovery slope representing microvascular reactivity were also collected at Tpre and Tpost For analysis the patients were divided into two groups overweight body mass index BMI 25 kgm2 and normal weight BMI 25
For this prospective observation investigation a total of 128 patients who underwent elective surgery under general anesthesia at Pusan National University Hospital between June 2018 and February 2021 were participated in this study Baseline StO2 on thenar eminence hemodynamics and laboratory profile were monitored before Tpre and 30 min after general anesthesia Tpost During vascular occlusion tests VOT the occlusion slope representing oxygen consumption of muscle and recovery slope representing microvascular reactivity were also collected at Tpre and Tpost For analysis the patients were divided into two groups overweight body mass index BMI 25 kgm2 and normal weight BMI 25
Detailed Description:
Preoperative laboratory findings were obtained Mean blood pressure MBP pulse oxygen saturation SpO2 heart rate HR skin temperature and VOT-derived measurements including baseline tissue oxygen saturation StO2 occlusion slope minimum StO2 time to minimum StO2 recovery slope maximum StO2 and time to baseline StO2 were recorded before Tpre and 30 min after general anesthesia Tpost
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1804-025-066 | OTHER | Pusan national university hospital | None |