Ignite Creation Date:
2024-05-06 @ 6:54 PM
Last Modification Date:
2024-10-26 @ 2:57 PM
Study NCT ID:
NCT05828537
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-06-18
First Post:
2023-04-12
Brief Title:
The Use of PEDI_ EAT 10 Score Versus Nurse Performed Screening in the Assessment of Post Extubation Dysphagia
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
the Use of PEDI_EAT 10 Score Versus Nurse Performed Screening in the Assessment of Post Extubation Dysphagia
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Invasive mechanical ventilation is one of the most common interventions in critically ill patients and is invariably characteristic if not defining of ICU therapeutic regimen Much attention has been paid to complications occurring during and because of mechanical ventilation such as nosocomial infections delirium and critical illness neuropathy and myopathy However an often underappreciated and minimally explored complication of mechanical ventilation is post-extubation dysphagia
Detailed Description:
Invasive mechanical ventilation is one of the most common interventions in critically ill patients and is invariably characteristic if not defining of ICU therapeutic regimen Much attention has been paid to complications occurring during and because of mechanical ventilation such as nosocomial infections delirium and critical illness neuropathy and myopathy However an often underappreciated and minimally explored complication of mechanical ventilation is post-extubation dysphagia
Post-extubation dysphagia PED is defined as the difficulty or inability to effectively and safely transfer food and liquid from the mouth to the stomach after extubation
As reported by Malandraki et al PED is more common in pediatric patients with an overall incidence of 29 and exceeds the 23 incidence reported in adults Another Australian context showed that 41 of critically-ill pediatric patients requiring endotracheal intubation eventually evolved PED with one-third of those patients experiencing silent aspiration
Using a prior pioneering prospective study of mechanically ventilated patients Zuercher et al evaluated 933 extubated patients of which 116 were screened for the presence of post-extubation dysphagia They analyzed pre-intubation characteristics to derive factors possibly associated with development of PED and found that pre-existing neurological disease emergency admission increased duration of mechanical ventilation increased duration of renal replacement therapy and higher severity of illness were associated with development of post- extubation dysphagia Interestingly increased BMI was associated with lower incidence of dysphagia
Because of the significant negative impact of post-extubation dysphagia on outcomes of pediatric patients early identification and intervention are crucial The scientific description of the phenomenon of post-extubation dysphagia in pediatric populations as a distinct pathological entity from the phenomenon in adult populations is considered a corner stone in the systematic exploration of the phenomenon Such systematic exploration has to date been limited
Post-extubation dysphagia PED is defined as the difficulty or inability to effectively and safely transfer food and liquid from the mouth to the stomach after extubation
As reported by Malandraki et al PED is more common in pediatric patients with an overall incidence of 29 and exceeds the 23 incidence reported in adults Another Australian context showed that 41 of critically-ill pediatric patients requiring endotracheal intubation eventually evolved PED with one-third of those patients experiencing silent aspiration
Using a prior pioneering prospective study of mechanically ventilated patients Zuercher et al evaluated 933 extubated patients of which 116 were screened for the presence of post-extubation dysphagia They analyzed pre-intubation characteristics to derive factors possibly associated with development of PED and found that pre-existing neurological disease emergency admission increased duration of mechanical ventilation increased duration of renal replacement therapy and higher severity of illness were associated with development of post- extubation dysphagia Interestingly increased BMI was associated with lower incidence of dysphagia
Because of the significant negative impact of post-extubation dysphagia on outcomes of pediatric patients early identification and intervention are crucial The scientific description of the phenomenon of post-extubation dysphagia in pediatric populations as a distinct pathological entity from the phenomenon in adult populations is considered a corner stone in the systematic exploration of the phenomenon Such systematic exploration has to date been limited
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None