Ignite Creation Date:
2024-05-06 @ 6:53 PM
Last Modification Date:
2024-10-26 @ 2:56 PM
Study NCT ID:
NCT05824013
Status:
COMPLETED
Last Update Posted:
2024-01-25
First Post:
2023-04-11
Brief Title:
Blood Coagulation Profile After Liver Resection
Sponsor:
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Organization:
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study Overview
Official Title:
Blood Caogulation Profile After Liver Resection Comparison of Conventional Blood Coagulation Tests With Thromboelastography
Status:
COMPLETED
Status Verified Date:
2023-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Liver resection is the treatment of choice in patients with primary or metastatic liver neoplasms benign liver neoplasms and numerous biliary diseases In these patients in the postoperative periodseveral factors can induce a transient alteration of the synthesis hepatic coagulation factors such as size of the lesion liver underlying liver disease eg malignancy pre-existing cirrhosis duration of both surgery and vascular clamping and blood loss So far some studies have shown that conventional coagulation tests indicate a hypocoagulable state which may lead to excessive transfusions of blood products or an increased risk of thromboembolic events related to delayed initiation of thromboprophylaxis in the postoperative period In an attempt to optimizing the state of coagulation recently there is increased interest for viscoelastic coagulation testing thromboelastography and rotational thromboelastometry The results of these studies have shown that these patients often have a hypercoagulable and non hypocoagulable profile as evidenced by conventional coagulation tests
the purpose of the study is to evaluate whether the combination of coagulation tests conventional systems and new thromboelastography can increase the quality of surveillance of the coagulation state after liver surgery in order to optimize the management of postoperative blood coagulation of these patients
the purpose of the study is to evaluate whether the combination of coagulation tests conventional systems and new thromboelastography can increase the quality of surveillance of the coagulation state after liver surgery in order to optimize the management of postoperative blood coagulation of these patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None