Viewing Study NCT05816044



Ignite Creation Date: 2024-05-06 @ 6:53 PM
Last Modification Date: 2024-10-26 @ 2:56 PM
Study NCT ID: NCT05816044
Status: COMPLETED
Last Update Posted: 2023-08-29
First Post: 2023-04-01

Brief Title: Evaluation of HALP Score in Preeclampsia
Sponsor: Prof Dr Cemil Tascıoglu Education and Research Hospital Organization
Organization: Prof Dr Cemil Tascıoglu Education and Research Hospital Organization

Study Overview

Official Title: Evaluation of HALP Score in Preeclampsia
Status: COMPLETED
Status Verified Date: 2023-08
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Preeclampsia is a serious condition that can occur during pregnancy and can pose problems for both the mother and the baby It occurs in approximately 2-8 of all pregnancies globally and is caused by issues with blood vessels leading to elevated blood pressure and other related health concerns Additionally insufficient nutrition and inflammation within the mothers body may contribute to the development of preeclampsia

The HALP score serves as a tool to assess various elements within the blood indicating inflammation or inadequate nutrition Although it has been utilized in other medical contexts its application during pregnancy remains limited The HALP score has been employed to predict the emergence of ailments such as heart disease and cancer Given that preeclampsia can stem from inflammation and poor nutrition the potential of the HALP score in predicting the likelihood of preeclampsia during pregnancy is being examined through research
Detailed Description: Preeclampsia is a hypertensive disorder affecting multiple body systems that poses a risk of maternal and fetal morbidity and mortality The global prevalence of preeclampsia is estimated to be around 2-8 of all pregnancies The pathophysiology of preeclampsia is complex and involves endothelial dysfunction and vasospasm resulting in hypertension and end-organ damage The development of preeclampsia is influenced by various factors including abnormalities in the placenta genetic factors and maternal immune system In addition poor maternal nutrition and inflammation have also been identified as potential contributors to the development of preeclampsia

The HALP score is a composite measure of hemoglobin albumin lymphocyte and platelet parameters that has been suggested as a possible indicator of systemic inflammation and malnutrition Although the HALP score has not been extensively studied in obstetrics it has been investigated in various medical fields as a predictor of adverse outcomes such as cardiovascular disease and cancer Given the significance of inflammation and malnutrition in the development of preeclampsia it is important to investigate the potential usefulness of the HALP score in predicting this condition

Due to the limited research on the application of the HALP score in obstetrics and the possible role of inflammation and malnutrition in the pathogenesis of preeclampsia a retrospective study is being planned to explore the potential utility of the HALP score as a predictor of preeclampsia By analyzing the relationship between the HALP score and the development of preeclampsia valuable insights can be obtained regarding the potential involvement of inflammation and malnutrition in the development of this disorder

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None