Ignite Creation Date:
2024-05-06 @ 6:52 PM
Last Modification Date:
2024-10-26 @ 2:56 PM
Study NCT ID:
NCT05812365
Status:
COMPLETED
Last Update Posted:
2023-05-09
First Post:
2023-04-02
Brief Title:
Best End-Expiratory and Driving-pressure for Individualized Flow Controlled Ventilation in Patients With COPD
Sponsor:
Universitätsklinikum Hamburg-Eppendorf
Organization:
Universitätsklinikum Hamburg-Eppendorf
Study Overview
Official Title:
Best End-Expiratory and Driving-Pressure for Individualized Flow Controlled Ventilation in Patients With COPD - an Observational Study
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patients with chronic obstructive pulmonary disease COPD have a significantly increased risk of postoperative pulmonary complications PPC Protective ventilation of the lungs could reduce the rate of PPC in patients with COPD It has been suggested that flow controlled ventilation FCV may be less invasive and more protective to the lungs than conventional ventilation in patients with COPD
The primary aim of this study is to determine a optimal individual ventilation setting for FCV in ten participants with COPD
The primary aim of this study is to determine a optimal individual ventilation setting for FCV in ten participants with COPD
Detailed Description:
The estimated worldwide chronic obstructive pulmonary disease COPD mean prevalence is 131 In 2015 32 million people died from COPD worldwide and estimates show that COPD will be the third leading cause of death in 2030 Patients with COPD are at high risk for postoperative pulmonary complications PPC It has been proposed that FCV might be less-invasive and more protective for the lungs than conventional ventilation in patients with COPD The pathophysiology of COPD is multifactorial with the collapse of the central airways having a major impact on the symptoms Minimizing the expiratory flow could prevent this airway pathology and thus be beneficial in the ventilation of patients with COPD
In the operation theater participants will be ventilated with flow controlled ventilation FCV Arterial blood gas analysis and electrical impedance tomography EIT will be measured
The aim of the study is to determine the best end-expiratory pressure and driving pressure assessed after anesthesia induction based on compliance and EIT parameters
In the operation theater participants will be ventilated with flow controlled ventilation FCV Arterial blood gas analysis and electrical impedance tomography EIT will be measured
The aim of the study is to determine the best end-expiratory pressure and driving pressure assessed after anesthesia induction based on compliance and EIT parameters
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None