Ignite Creation Date:
2024-05-06 @ 6:52 PM
Last Modification Date:
2024-10-26 @ 2:56 PM
Study NCT ID:
NCT05814198
Status:
COMPLETED
Last Update Posted:
2023-08-29
First Post:
2023-04-01
Brief Title:
Evaluation of HALP Score in Distinction Between FGR and SGA
Sponsor:
Prof Dr Cemil Tascıoglu Education and Research Hospital Organization
Organization:
Prof Dr Cemil Tascıoglu Education and Research Hospital Organization
Study Overview
Official Title:
Evaluation of Hemoglobin Albumin Lymphocyte Platelet HALP Score in Distinction Between Fetal Growth Restriction FGR and Small for Gestational Age SGA
Status:
COMPLETED
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Fetal Growth Restriction FGR and Small for Gestational Age SGA are two conditions that can happen when a baby doesnt grow as much as expected during pregnancy FGR is caused by things like problems with the mothers nutrition and inflammation while SGA is usually because of genetic and other factors
Its important to know if a baby has FGR or SGA because FGR babies can have more health problems and are at risk of dying before or shortly after birth SGA babies are usually healthy but they might have more health problems later in life
Doctors can use a simple blood test called the HALP score to see if a mother has problems with her nutrition and inflammation However it hasnt been studied for FGR and SGA We want to study if the HALP score can help us tell if a baby has FGR or SGA by looking at the mothers blood test results
Its important to know if a baby has FGR or SGA because FGR babies can have more health problems and are at risk of dying before or shortly after birth SGA babies are usually healthy but they might have more health problems later in life
Doctors can use a simple blood test called the HALP score to see if a mother has problems with her nutrition and inflammation However it hasnt been studied for FGR and SGA We want to study if the HALP score can help us tell if a baby has FGR or SGA by looking at the mothers blood test results
Detailed Description:
Fetal Growth Restriction FGR and Small for Gestational Age SGA are two conditions that are commonly encountered in obstetrics FGR is defined as a condition in which the fetus is smaller than expected for its gestational age and its pathophysiology is thought to be influenced by both maternal inflammation and nutritional status On the other hand SGA is a condition in which the fetus is smaller than expected but its pathophysiology is primarily attributed to constitutional and genetic factors
It is important to distinguish between FGR and SGA because FGR is associated with a higher risk of adverse fetal and neonatal outcomes including morbidity and mortality In contrast SGA infants are generally healthy but may have a higher risk of long-term health problems such as hypertension and diabetes
The HALP score is a simple and easily calculated index that is based on the levels of hemoglobin lymphocytes albumin and platelets It has been shown to be informative about the nutritional and inflammatory status in various medical fields However its use in obstetrics is limited and its potential to distinguish between FGR and SGA has not been studied
Given that maternal inflammation and nutritional status are also involved in the pathophysiology of FGR it is possible that the HALP score could be useful in distinguishing between FGR and SGA Therefore we plan to investigate the potential of the HALP score in differentiating between these two conditions
It is important to distinguish between FGR and SGA because FGR is associated with a higher risk of adverse fetal and neonatal outcomes including morbidity and mortality In contrast SGA infants are generally healthy but may have a higher risk of long-term health problems such as hypertension and diabetes
The HALP score is a simple and easily calculated index that is based on the levels of hemoglobin lymphocytes albumin and platelets It has been shown to be informative about the nutritional and inflammatory status in various medical fields However its use in obstetrics is limited and its potential to distinguish between FGR and SGA has not been studied
Given that maternal inflammation and nutritional status are also involved in the pathophysiology of FGR it is possible that the HALP score could be useful in distinguishing between FGR and SGA Therefore we plan to investigate the potential of the HALP score in differentiating between these two conditions
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None