Ignite Creation Date:
2024-05-06 @ 6:52 PM
Last Modification Date:
2024-10-26 @ 2:56 PM
Study NCT ID:
NCT05816889
Status:
RECRUITING
Last Update Posted:
2024-05-24
First Post:
2023-04-04
Brief Title:
Investigation of Exercise Capacity Muscle Oxygenation and Physical Activity Level in Parkinsons Patients
Sponsor:
Gazi University
Organization:
Gazi University
Study Overview
Official Title:
Investigation of Exercise Capacity Muscle Oxygenation and Physical Activity Level in Parkinsons Patients
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary aim of this study is to compare maximum and functional exercise capacity and muscle oxygenation during exercise test in patients with Parkinsons disease The secondary aim is to evaluate respiratory functions respiratory muscle strength and endurance peripheral muscle strength physical activity level shortness of breath and fatigue in Parkinsons patients and compare with healthy individuals
Detailed Description:
Parkinsons disease is the second most common neurodegenerative disease The main motor symptoms in Parkinsons disease are tremor rigidity bradykinesia and decreased postural reflexes and respiratory problems are seen that cause mortality Disturbances in the control of the epiglottis laryngeal and pharyngeal muscles may cause aspiration pneumonia The coughing or exhalation reflex requires coordinated motor activity and inadequate airway defense poses a risk for pneumonia Upper airway obstruction may occur due to rigidity and fatigue in the thyroarytenoid muscles It can cause a decrease in lung volumes and thus the development of restrictive respiratory function abnormality
Pulmonary functions exercise capacity respiratory muscle strength and endurance peripheral muscle strength physical activity level and fatigue were affected in patients The number of studies on these subjects is limited
Mitochondrial dysfunction in Parkinsons patients has been proven in several studies There is no study in the literature evaluating muscle oxygenation at rest and during exercise in Parkinsons patients
The primary aim of this study is to compare maximum and functional exercise capacity and muscle oxygenation during exercise test in patients with Parkinsons disease The secondary aim is to evaluate respiratory functions respiratory muscle strength and endurance peripheral muscle strength physical activity level shortness of breath and fatigue in Parkinsons patients and compare with healthy individuals
The study was planned cross-sectional Patients with Parkinson Disease referred to the Cardiopulmonary Rehabilitation Unit of Gazi University Physiotherapy and Rehabilitation Department by the physicians of the Neurology Department of Gazi University Faculty of Medicine will be included in the study At least 26 patients with Parkinson Disease and at least 26 healthy controls of similar age and sex will be evaluated in the study The assessments will be completed in two days
Upper extremity exercise capacity 6 minutes Pegboard and Ring Test muscle oxygenation Moxy monitor functional exercise capacity6 minutes walk test respiratory functions spirometer respiratory muscle strength mouth pressure measurement respiratory muscle endurance incremental threshold loading test peripheral muscle strength dynamometer physical activity level multi-sensor activity monitor and fatigue Parkinsons Fatigue Scale will be evaluated
Pulmonary functions exercise capacity respiratory muscle strength and endurance peripheral muscle strength physical activity level and fatigue were affected in patients The number of studies on these subjects is limited
Mitochondrial dysfunction in Parkinsons patients has been proven in several studies There is no study in the literature evaluating muscle oxygenation at rest and during exercise in Parkinsons patients
The primary aim of this study is to compare maximum and functional exercise capacity and muscle oxygenation during exercise test in patients with Parkinsons disease The secondary aim is to evaluate respiratory functions respiratory muscle strength and endurance peripheral muscle strength physical activity level shortness of breath and fatigue in Parkinsons patients and compare with healthy individuals
The study was planned cross-sectional Patients with Parkinson Disease referred to the Cardiopulmonary Rehabilitation Unit of Gazi University Physiotherapy and Rehabilitation Department by the physicians of the Neurology Department of Gazi University Faculty of Medicine will be included in the study At least 26 patients with Parkinson Disease and at least 26 healthy controls of similar age and sex will be evaluated in the study The assessments will be completed in two days
Upper extremity exercise capacity 6 minutes Pegboard and Ring Test muscle oxygenation Moxy monitor functional exercise capacity6 minutes walk test respiratory functions spirometer respiratory muscle strength mouth pressure measurement respiratory muscle endurance incremental threshold loading test peripheral muscle strength dynamometer physical activity level multi-sensor activity monitor and fatigue Parkinsons Fatigue Scale will be evaluated
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None