Ignite Creation Date:
2024-05-06 @ 6:51 PM
Last Modification Date:
2024-10-26 @ 2:55 PM
Study NCT ID:
NCT05802732
Status:
RECRUITING
Last Update Posted:
2023-04-06
First Post:
2023-03-25
Brief Title:
Stool Antigen In Diagnosis Of Helicobacter Pylori
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Diagnostic Accuracy Of Stool Antigen In Diagnosis Of Helicobacter Pylori Infection In Children
Status:
RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Helicobacter pylori is among the most common bacterial infections in humans Helicobacter pylori is a Gram-negative S -shaped rod The most likely mode of transmission is fecal-oral or oral-oral Helicobacter pylori infection is acquired in early life and continues to have a high prevalence especially in developing countries Growing antibiotic-resistant strains necessitate adapted treatments The majority of children with Helicobacter pylori infection remain asymptomatic although a percentage of the infected children do develop Helicobacter pylori-associated diseases Helicobacter pylori is closely associated with the development of gastritis gastric or duodenal ulcers Helicobacter pylori infection can manifest with abdominal pain or vomiting and less often refractory iron deficiency anemia or growth retardation Helicobacter pylori can be associated though rarely with chronic autoimmune thrombocytopenia Anemia idiopathic thrombocytopenic purpura short stature and sudden infant death syndrome SIDS have also been reported as possible extra-gastric manifestations of Helicobacter pylori infection The diagnosis of Helicobacter pylori infection is made histologically by demonstrating the organism in the biopsy specimens 13 C-urea breath tests and stool antigen tests are reliable noninvasive methods of detecting Helicobacter pylori infection in patients who do not require endoscopic evaluation However some guidelines recommend that non-invasive assessment methods are reserved to determine whether Helicobacter pylori has been eradicated not for diagnosis However Helicobacter pylori-associated gastritis may however be an incidental histopathologic finding during upper endoscopy performed for unrelated indications such as the diagnosis of inflammatory bowel disease or celiac disease
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None