Ignite Creation Date:
2024-05-06 @ 6:51 PM
Last Modification Date:
2024-10-26 @ 2:55 PM
Study NCT ID:
NCT05803447
Status:
COMPLETED
Last Update Posted:
2023-04-07
First Post:
2023-01-24
Brief Title:
Analysis of Parameters Indicating the Intensity of Suicidal Behavior in Psychiatric Patients
Sponsor:
Medical University of Bialystok
Organization:
Medical University of Bialystok
Study Overview
Official Title:
Analysis of Parameters Indicating the Intensity of Suicidal Behavior in Patients Suffering From Depression and Schizophrenia
Status:
COMPLETED
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study was to analyse the level of cognitive functioning of patients with history of suicidal behaviour suffering from depression and schizophrenia and to evaluate their oxidative stress parameters and selected biochemical parameters on the basis of bloodwork
Detailed Description:
The study was conducted among 120 patients hospitalized in the Department of Psychiatry of the UMB Medical University of Białystok Every participant gave their own voluntary and informed written consent Blood parameters tests were performed in the Diagnostic Laboratory of the Universitys Clinical Hospital and in the Department of Hygiene Epidemiology and Ergonomics of the Medical University of Białystok In the first stage of the study an MINI 702 interview was conducted with each patient to verify the intensification of suicidal behaviour Based on the scores the patients were classified into one of eight groups no suicidal behaviour group G0K G0M group experiencing suicidal thoughts without a tendency of implementation G1K G1M group experiencing suicidal thoughts with a tendency of implementation G2K G2M group after a suicide attempt G3K G3MThe second stage of the study consisted of biochemical blood tests where concentrations of vitamin D3 B12 folic acid sodium potassium calcium magnesium chlorine total cholesterol LDL and HDL fractions TG and metabolites of the oxidative stress pathway were determined The following concentrations were determined dityrosine AUFmg protein TOS nmol H2O2 Equivmg protein TAC umolmg protein OSI TOSTAC ratio FRAP μmolmg protein GPx mUmg protein SOD mUmg protein CAT nmol H2O2minmg protein AOPP nmolmg protein NO nmolmg protein GSH μgmg protein The third stage of the study consisted of the participants completing a CogState computerized test to verify their cognitive functioning The following cognitive functions were assessed psychomotor drive DET metastability of attention IDN verbal memory retrieval of learned material ISLR and verbal learning and memory ISL visual learning and memory OCL processing speed GMCT visual memory including deferred retrieval GMR executive functions SETS and GML working memory ONB TWOB
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None