Ignite Creation Date:
2024-05-06 @ 6:50 PM
Last Modification Date:
2024-10-26 @ 2:56 PM
Study NCT ID:
NCT05807646
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-02-15
First Post:
2023-03-29
Brief Title:
Reduced Dissemination of Tumor Cells With Primary Ligation of the Inferior Mesenteric Vein in Rectal Cancer Patients
Sponsor:
Sichuan Cancer Hospital and Research Institute
Organization:
Sichuan Cancer Hospital and Research Institute
Study Overview
Official Title:
Effect of Ligation Sequence of the Inferior Mesenteric Artery and Vein on Circulating Tumor Cells and Survival in Laparoscopic Rectal Cancer Surgery a Prospective Multicenter Randomized Controlled Study ARVECTS
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Effect of ligation sequence of the inferior mesenteric artery and vein on circulating tumor cells and survival in laparoscopic rectal cancer surgery a prospective multicenter randomized controlled study ARVECTS
Detailed Description:
Several studies have demonstrated that the presence of circulating tumor cells CTCs in the peripheral blood can be a surrogate biomarker to predict recurrence and prognosis of rectal cancer CTCs are released from the primary tumor into the bloodstream and have the potential to spread to distant sites and develop into micro-metastatic deposits Numerous studies have demonstrated that surgical manipulation could promote the dissemination of tumor cells into the circulation Theoretically the potential risk of tumor cell dissemination can theoretically be minimized if the effluent vein was ligated first However there is no regulation in the current guidelines on the sequence of ligation of the inferior mesenteric artery and vein during rectal cancer surgery owing to a lack of sufficient evidence This multi-center randomized controlled trial is to investigate effect of ligation sequence of the inferior mesenteric artery and vein on circulating tumor cells and survival in laparoscopic rectal cancer surgery
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None