Ignite Creation Date:
2024-05-06 @ 6:50 PM
Last Modification Date:
2024-10-26 @ 2:56 PM
Study NCT ID:
NCT05808465
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2023-04-14
First Post:
2023-03-30
Brief Title:
Different Methods of Cardiac MRI in Assessment of Estimated Corrected Ejection Fraction in Valvular Heart Diseases
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Comparative Study Between Phase ContrastModified Simpson Rule and Myocardial Strain Analysis Methods of Cardiac MRI in Assessment of Estimated Corrected Ejection Fraction in Valvular Heart Disease
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2023-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Comparative study between Phase Contrast Modified Simpson Rule and Myocardial Strain Analysis methods of Cardiac Magnetic Resonance Imaging in assessment of Corrected Estimated Ejection Fraction in Valvular Heart Disease To Evaluate the diagnostic accuracy of different methods of cardiac MRI to assess estimated corrected ejection fraction in valvular heart diseases
Detailed Description:
Valvular heart diseases are common cardiovascular conditions that account for 10 to 20 of all cardiac surgical procedures
In routine clinical practiceleft ventricular performance is one of the most important prognostic factors in valvular heart diseaseswhether treated medically or surgicallyIt gives valuable information that may be useful in the selection of therapy or determination of the optimal time for intervention
Cardiovascular MR has grown to be a widely used clinical tool for evaluating cardiovascular diseaseit is designed to assess cardiovascular morphologyventricular functionmyocardial perfusiontissue characterizationflow quantification and coronary artery diseaseUtilization of CMR for evaluation of valvular regurgitation has recently been recognized as part of the American Society of Echocardiography ASE and the Society of Cardiovascular Magnetic Resonance SCMR recommendations In previous guidelinesCMR was only advocated in valvular disease in situations where echocardiographic evaluation was insufficient or inconclusiveHoweverwith excellent spatial and temporal resolutionCMR may provide added benefits for valvular evaluationincluding visualization of valve structure direct measurements of flowassessment of ventricular volumes and quantification of regurgitant volumes and fractions Among CMR techniques are
Phase-contrast MRI a technique with which flow can be measured accurately with flexible spatial and temporal resolution The severity of valvular disease can be assessed and quantified with Phase contrast MRI providing the ability to quantify peak velocities and flow across the valves
Simpson rule a method to calculate cardiac global function parameters out of multiple single slicesquantifying volumetric indices of the heart directly from the 3 dimensional dataset an ability that sets it apart from other modalities End-Diastolic VolumeEnd-Systolic VolumeStroke VolumeEjection Fraction and Ventricular Mass can be obtained using Simpson rule making it able to determine these measurements in the right side as well as the left
Myocardial Strain Analysis provides higher spatial resolution than echocardiography and is useful for the quantitative assessment of cardiac functionMeasurement of left ventricular volume parameters such as ejection fraction end diastolic volume end systolic volume stroke volume cardiac output cardiac index and contractile function are possible in analysis using MRI
In routine clinical practiceleft ventricular performance is one of the most important prognostic factors in valvular heart diseaseswhether treated medically or surgicallyIt gives valuable information that may be useful in the selection of therapy or determination of the optimal time for intervention
Cardiovascular MR has grown to be a widely used clinical tool for evaluating cardiovascular diseaseit is designed to assess cardiovascular morphologyventricular functionmyocardial perfusiontissue characterizationflow quantification and coronary artery diseaseUtilization of CMR for evaluation of valvular regurgitation has recently been recognized as part of the American Society of Echocardiography ASE and the Society of Cardiovascular Magnetic Resonance SCMR recommendations In previous guidelinesCMR was only advocated in valvular disease in situations where echocardiographic evaluation was insufficient or inconclusiveHoweverwith excellent spatial and temporal resolutionCMR may provide added benefits for valvular evaluationincluding visualization of valve structure direct measurements of flowassessment of ventricular volumes and quantification of regurgitant volumes and fractions Among CMR techniques are
Phase-contrast MRI a technique with which flow can be measured accurately with flexible spatial and temporal resolution The severity of valvular disease can be assessed and quantified with Phase contrast MRI providing the ability to quantify peak velocities and flow across the valves
Simpson rule a method to calculate cardiac global function parameters out of multiple single slicesquantifying volumetric indices of the heart directly from the 3 dimensional dataset an ability that sets it apart from other modalities End-Diastolic VolumeEnd-Systolic VolumeStroke VolumeEjection Fraction and Ventricular Mass can be obtained using Simpson rule making it able to determine these measurements in the right side as well as the left
Myocardial Strain Analysis provides higher spatial resolution than echocardiography and is useful for the quantitative assessment of cardiac functionMeasurement of left ventricular volume parameters such as ejection fraction end diastolic volume end systolic volume stroke volume cardiac output cardiac index and contractile function are possible in analysis using MRI
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None