Ignite Creation Date:
2024-05-06 @ 6:49 PM
Last Modification Date:
2024-10-26 @ 2:55 PM
Study NCT ID:
NCT05793437
Status:
COMPLETED
Last Update Posted:
2024-02-01
First Post:
2023-03-03
Brief Title:
Effects of Permissive Hypercapnia on Concentration of Postoperative Plasma Neurofilament Light
Sponsor:
Affiliated Hospital of Jiaxing University
Organization:
Affiliated Hospital of Jiaxing University
Study Overview
Official Title:
Effects of Permissive Hypercapnia on Concentration of Postoperative Plasma Neurofilament Light in Elderly Patients Undergoing Laparoscopic SurgeryA Prospective Randomized Controlled Study
Status:
COMPLETED
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to conduct a prospective single-center randomized controlled study to investigate the changes of plasma NFL concentration in patients undergoing laparoscopic surgery with mild hypercapnia and further explore its impact on the central nervous system
Detailed Description:
Plasma NFL concentrations were measured preoperatively and 1 day postoperatively
Secondary endpointsCAM Confusion Assessment Method is conducted to check the subjects baseline cognitive function preoperative day and 1 day postoperatively to assess whether delirium occurs
Secondary endpointsCAM Confusion Assessment Method is conducted to check the subjects baseline cognitive function preoperative day and 1 day postoperatively to assess whether delirium occurs
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None