Ignite Creation Date:
2024-05-06 @ 6:49 PM
Last Modification Date:
2024-10-26 @ 2:55 PM
Study NCT ID:
NCT05792904
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-03-31
First Post:
2023-03-17
Brief Title:
Factors Associated With Complicated Pneumonia in Paedatrics
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Factors Associated With Complicated Pneumonia in Paedatrics
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Detecting Factors associated with complicated pneumonia in pediatrics
Detailed Description:
Community acquired pneumonia is the cause of morbidity and mortality in children worldwide complication of Community acquired pneumonia in paedatrics include para -pneumonic pleural effusion empyema necrotizing pneumonia and lung abscess Sawicki GS2008 Pediatric para-pneumonic pleural effusion and empyema are considered different stages of the same pathophysiological process in which pleural inflammation causes fluid to accumulate in the pleural cavity Necrotizing pneumonia results from pulmonary necrosis and tissue liquefaction Ira Erlichman MD2017 Recent reports have characterized the clinical presentation of this complication and have shown favorable outcomes in children Sawicki GS2008 Complicated pneumonia was defined as clinical pneumonia and the presence of pleural effusion empyema EMP or Para-pneumonic childhood EMP was defined as the presence of pus purulent fluid andor WBC count5000 permm3 or bacteria in the pleural fluid
PPE was defined by pleural fluid not fitting criteria of EMP and the diagnosis of NP was made by the presence of multiple cavity gas-filled spaces within a pulmonary consolidation on chest X-rays or liquefaction of lung tissue according to CT scans as reviewed by a pediatric radiologist Ira Erlichman MD 2017 Among patients with pneumonia AS MANY AS half may develop pleural effusions ie fluid in THE PLEURAL SPACE of these 5-10 MAY DEVELOP EMPYEMAN Ingeneral complicated pneumonia refers to pneumonia accompanied by pleural effusion Byington CL2010 Empyema is a serious COMPLICATIO characterized by pus and bacteria in the pleural space which may progress to necrosis cavitation or fistulas in the thoracic cavity S pneumoniae is the most common cause of complicated pneumonia in children an M A Fletcher ETT 2014 Empyema among children age below 19 years in Utah USA 1994-2007 and Australia1998-2010ranged from 09 to 125 per 100000 Byington CL2010the incidence was highest in children aged 0-4 and tend to increase over time Strachan RE2013
PPE was defined by pleural fluid not fitting criteria of EMP and the diagnosis of NP was made by the presence of multiple cavity gas-filled spaces within a pulmonary consolidation on chest X-rays or liquefaction of lung tissue according to CT scans as reviewed by a pediatric radiologist Ira Erlichman MD 2017 Among patients with pneumonia AS MANY AS half may develop pleural effusions ie fluid in THE PLEURAL SPACE of these 5-10 MAY DEVELOP EMPYEMAN Ingeneral complicated pneumonia refers to pneumonia accompanied by pleural effusion Byington CL2010 Empyema is a serious COMPLICATIO characterized by pus and bacteria in the pleural space which may progress to necrosis cavitation or fistulas in the thoracic cavity S pneumoniae is the most common cause of complicated pneumonia in children an M A Fletcher ETT 2014 Empyema among children age below 19 years in Utah USA 1994-2007 and Australia1998-2010ranged from 09 to 125 per 100000 Byington CL2010the incidence was highest in children aged 0-4 and tend to increase over time Strachan RE2013
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None