Ignite Creation Date:
2024-05-06 @ 6:49 PM
Last Modification Date:
2024-10-26 @ 2:55 PM
Study NCT ID:
NCT05792982
Status:
COMPLETED
Last Update Posted:
2023-03-31
First Post:
2023-03-17
Brief Title:
Serum Fibroblast Growth Factor-21 Levels During Prolonged Fasting
Sponsor:
Hacettepe University
Organization:
Hacettepe University
Study Overview
Official Title:
Fluctuations of Serum Fibroblast Growth Factor-21 Levels During Prolonged Fasting in Male Adults
Status:
COMPLETED
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The investigators hypothesized that serum FGF21 levels would increase with prolongation of the fasting period The investigators also hypothesized that food intake and body composition would change The study was conducted with 12 healthy male adults A questionnaire was administered at the beginning of the study Anthropometric measurements dietary intake and physical activities were recorded and blood samples were taken before during and after Ramadan
Detailed Description:
The aim of this study was to determine the effects of hunger on serum Fibroblast Growth Factor 21 FGF21 levels nutritional status and anthropometric measurements of adult males during fasting FGF21 is a significant protein in the process of adaption to fasting due to its effects on liver adipose tissue and brain A total of 12 healthy individuals with normal body mass index between the ages of 18 to 35 participated to this cross-sectional study All participants provided written informed consent Sample size determined with power analysis A questionnaire was administered in order to determine individuals general characteristics nutrition habits and smoking and alcohol habits Anthropometric measurements 24 hours dietary recall and physical activities were recorded and blood samples were taken four times in following periods before Ramadan first week of Ramadan third week of Ramadan and two weeks after Ramadan Serum FGF21 levels were determined by ELISA Enzyme-Linked Immunosorbent Assay Mean energy and nutrient intake were calculated by BEBIS Nutrition Information System and results were compared with Recommended Dietary Allowances RDA Paired samples t-test and Wilcoxon-signed rank test were used to explore differences The study was approved by Hacettepe University Non-Interventional Clinical Research Ethics Board
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None