Ignite Creation Date:
2024-05-06 @ 6:48 PM
Last Modification Date:
2024-10-26 @ 2:55 PM
Study NCT ID:
NCT05791188
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-04-04
First Post:
2023-03-16
Brief Title:
Electrolyte Disorders in Prediabetics and in Patients With Type 2 Diabetes Mellitus
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Electrolyte Disorders in Prediabetics and in Patients With Type 2 Diabetes Mellitus
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of the study is to assess serum sodium Na potassium K magnesium Mg2 calcium Ca2 and chloride Cl- levels in patients who are prediabetic diabetics and diabetic with complications Diabetes mellitus type 2
Detailed Description:
Diabetes mellitus is a chronic disease that imposes enormous socioeconomic burdens attributable to complications of various bodily systems Diabetes affected 463 million people 93 of all people in 2019 and will affect 700 million 109 by 2045
According to the International Diabetes Federation IDF the prevalence of diabetes mellitus among Egyptian adults is 152 which may be an underestimation Therefore diabetes mellitus should be thoroughly explored in terms of its risk factors prevention treatment and consequences Moreover the general population should be aware of and well informed about all aspects of diabetes
Prediabetes is a precursor before the diagnosis of diabetes mellitus Adults with prediabetes often may show no signs or symptoms of diabetes but will have blood glucose levels higher than normal The normal blood glucose level is between 70 - 99 mgdL In patients with prediabetes the blood glucose levels elevated between 110 - 125 mgdL
Once the patient is diagnosed as prediabetes he should be checked for progression to type 2 diabetes every one to two years So early detection of prediabetes and so lifestyle changes through improved nutrition and physical activity are the first line treatment for preventing the transition from prediabetes to diabetes which can be as high as 70
A normal HbA1C level is below 57 a level of 57-64 indicates prediabetes and a level of 65 or more indicates diabetes Within the 57-64 prediabetes range the higher HbA1C the greater risk is for developing type 2 diabetes
Serum electrolytes are important cofactors for multiple enzymes and play a pivotal role in many key biological and physiological processes including glucose metabolism The excess or deficiency of these electrolytes was found to be linked to deleterious metabolism status
Diabetic patients frequently develop a constellation of electrolyte disorders These disturbances are particularly common in decompensated diabetics especially in the context of diabetic ketoacidosis or nonketotic hyperglycemic hyperosmolar syndrome
According to the International Diabetes Federation IDF the prevalence of diabetes mellitus among Egyptian adults is 152 which may be an underestimation Therefore diabetes mellitus should be thoroughly explored in terms of its risk factors prevention treatment and consequences Moreover the general population should be aware of and well informed about all aspects of diabetes
Prediabetes is a precursor before the diagnosis of diabetes mellitus Adults with prediabetes often may show no signs or symptoms of diabetes but will have blood glucose levels higher than normal The normal blood glucose level is between 70 - 99 mgdL In patients with prediabetes the blood glucose levels elevated between 110 - 125 mgdL
Once the patient is diagnosed as prediabetes he should be checked for progression to type 2 diabetes every one to two years So early detection of prediabetes and so lifestyle changes through improved nutrition and physical activity are the first line treatment for preventing the transition from prediabetes to diabetes which can be as high as 70
A normal HbA1C level is below 57 a level of 57-64 indicates prediabetes and a level of 65 or more indicates diabetes Within the 57-64 prediabetes range the higher HbA1C the greater risk is for developing type 2 diabetes
Serum electrolytes are important cofactors for multiple enzymes and play a pivotal role in many key biological and physiological processes including glucose metabolism The excess or deficiency of these electrolytes was found to be linked to deleterious metabolism status
Diabetic patients frequently develop a constellation of electrolyte disorders These disturbances are particularly common in decompensated diabetics especially in the context of diabetic ketoacidosis or nonketotic hyperglycemic hyperosmolar syndrome
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None