Ignite Creation Date:
2024-05-06 @ 6:47 PM
Last Modification Date:
2024-10-26 @ 2:55 PM
Study NCT ID:
NCT05788952
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-03-29
First Post:
2023-03-15
Brief Title:
The Role of Intestinal and Vaginal Microbiota Estrogenic Activity Metabolic Profile Nutritional Status in Endometriosis
Sponsor:
Universidade Nova de Lisboa
Organization:
Universidade Nova de Lisboa
Study Overview
Official Title:
UNRAVEL - The Role of Intestinal and Vaginal Microbiota Estrogenic Activity Metabolic Profile Nutritional Status in Symptom Severity and Quality of Life of Portuguese Women With Endometriosis - an Exploratory Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
UNRAVEL
Brief Summary:
Endometriosis EMs is one of the most prevalent benign gynaecological diseases and it is an inflammatory oestrogen-dependent condition Several authors have proposed that anatomical genetic endocrine immunological environmental hormonal and inflammatory factors may influence tissue implantation outside the uterus An approach to EMs aetiology that involves defining a profile to the vaginal and gut microbiota estrogenic activity and exposure to xenoestrogens and also metabolic and nutritional status of women with EMs may help identify some important patterns to better characterize this disease and also to define more personalized nutritional strategies also predicting patients predisposition to therapy success This is an observational study on premenopausal woman diagnosed with EMs who will be recruited on the outpatient gynaecology appointment to evaluate the vaginal and intestinal microbiome measure the total estrogenic activity assess the metabolic biomarkers and the nutritional status
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None