Viewing Study NCT05776563



Ignite Creation Date: 2024-05-06 @ 6:45 PM
Last Modification Date: 2024-10-26 @ 2:54 PM
Study NCT ID: NCT05776563
Status: RECRUITING
Last Update Posted: 2024-04-16
First Post: 2023-03-06

Brief Title: Reversibility of Brain Glucose Transport in Type 2 Diabetes Mellitus T2DM
Sponsor: Yale University
Organization: Yale University

Study Overview

Official Title: Reversibility of Brain Glucose Transport and Metabolism in T2DM
Status: RECRUITING
Status Verified Date: 2024-07
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: The goal of this clinical trial is to learn about the effects of high blood glucose levels in the brain and assess if the changes seen in individuals with poorly control T2DM can be reversed with good glucose control

The main questions it aims to answer are

To determine whether abnormalities in brain glucose transport seen in individuals with uncontrolled diabetes can be improved with better glucose control
Assess which factors duration of diabetes mellitus DM and glycemic control contribute to changes in glucose transport

Participants will have

A screening visit
placement of a continuous glucose monitor CGM 2 weeks before the first magnetic resonance spectroscopy MRS at week 0
Additional visitsphone calls for intensification of diabetes management and nutrition visits
Second magnetic resonance spectroscopy MRS at week 12
Detailed Description: None

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None
Secondary IDs
Secondary ID Type Domain Link
1K23DK132517-01A1 NIH None httpsreporternihgovquickSearch1K23DK132517-01A1