Ignite Creation Date:
2024-05-06 @ 6:44 PM
Last Modification Date:
2024-10-26 @ 2:53 PM
Study NCT ID:
NCT05767528
Status:
RECRUITING
Last Update Posted:
2023-03-14
First Post:
2023-02-15
Brief Title:
Clinical Study of Neoadjuvant Therapy Outcome Prediction of Muscle-invasive Bladder Cancer Based on PTC Drug Sensitivity Detection
Sponsor:
Chinese PLA General Hospital
Organization:
Chinese PLA General Hospital
Study Overview
Official Title:
Clinical Study of Neoadjuvant Therapy Outcome Prediction of Muscle-invasive Bladder Cancer Based on PTC Drug Sensitivity Detection
Status:
RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study investigators plan to conduct the 3D in vitro culture PTC drug sensitivity testing of fresh tumor specimen which obtained by endoscopic biopsy or other methods Through assessing the consistency between the testing results and the patients neoadjuvant treatment outcomes they would evaluate the accuracy of PTC drug sensitivity testing and its application value in the individualized precision medicine for muscle-invasive bladder carcinoma
Detailed Description:
This is a prospective observational study In this study researchers propose to enroll 40 participants above 18 years of age with muscle-invasive bladder carcinoma who are going to receive the neoadjuvant therapy before surgery Collecting fresh tumor samples for PTC drug sensitivity testing conducting neoadjuvant therapy for the subjects simultaneously By combining PTC prediction results with the patients clinical treatment process and medication feedback researchers could estimate the accuracy of PTC drug sensitivity testing Completion of this research would provide real-world figures to support for the clinical application for PTC drug sensitivity testing and a method is going to be established to guide the clinical treatment regimen for patients with muscle-invasive bladder carcinoma
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None