Ignite Creation Date:
2024-05-06 @ 6:44 PM
Last Modification Date:
2024-10-26 @ 2:53 PM
Study NCT ID:
NCT05766293
Status:
COMPLETED
Last Update Posted:
2023-03-13
First Post:
2023-02-14
Brief Title:
ESWT on Human Gingival Fibroblasts
Sponsor:
Dr Prabhuji MLV
Organization:
Krishnadevaraya College of Dental Sciences Hospital
Study Overview
Official Title:
Application of Extracorporeal Shockwaves on Human Gingival Fibroblasts in Vitro Study
Status:
COMPLETED
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ESWT
Brief Summary:
The idea of treating different deformities or diseases in the maxillofacial region with Extracorporeal Shockwave Therapy ESWT has recently become popular Shockwave therapy was first introduced in Germany in 1980s and has been widely used in medical practice for the management of urolithiasis cholelithiasis and in head and neck region for sialolithiasis
The present study Application of Extracorporeal Shock Wave Therapy on human gingival derived fibroblasts In-vitro study was done to explore and evaluate the effect of shockwaves Further these cells were assessed for Cell - Cell interaction and Cell Viability
In this in-vitro study 20 fibroblast cells were included 10 samples were considered for Control group and the remaining 10 samples were considered as Test group Extracorporeal shockwave was applied to the Test samples They were further analysed
The present study Application of Extracorporeal Shock Wave Therapy on human gingival derived fibroblasts In-vitro study was done to explore and evaluate the effect of shockwaves Further these cells were assessed for Cell - Cell interaction and Cell Viability
In this in-vitro study 20 fibroblast cells were included 10 samples were considered for Control group and the remaining 10 samples were considered as Test group Extracorporeal shockwave was applied to the Test samples They were further analysed
Detailed Description:
BACKGROUND
Improved understanding of human biology at the molecular level scientific and technologic advances are emerging aspects in dentistry The idea of treating different deformities or diseases in the maxillofacial region with Extracorporeal Shockwave Therapy ESWT has recently become popular Shockwave therapy was first introduced in Germany in 1980s and has been widely used in medical practice for the management of urolithiasis cholelithiasis and in head and neck region for sialolithiasis
AIM
The present study Application of Extracorporeal Shock Wave Therapy on human gingival tissue derived fibroblasts In-vitro study was done to explore and evaluate the effect of shockwaves Further fibroblast cells were assessed for Cell - Cell interaction and Cell Viability
MATERIALS AND METHODS
In this in-vitro study 20 fibroblast cells were included 10 samples were considered for Control group and the remaining 10 samples were considered as Test group Extracorporeal shockwave was applied to the Test samples They were further analysed using wound scratch assay which was used to assess Cell proliferative rate and scratch closure through live imaging MTT assay and ATP assay was used to determine Cell viability after exposure to shockwaves
Improved understanding of human biology at the molecular level scientific and technologic advances are emerging aspects in dentistry The idea of treating different deformities or diseases in the maxillofacial region with Extracorporeal Shockwave Therapy ESWT has recently become popular Shockwave therapy was first introduced in Germany in 1980s and has been widely used in medical practice for the management of urolithiasis cholelithiasis and in head and neck region for sialolithiasis
AIM
The present study Application of Extracorporeal Shock Wave Therapy on human gingival tissue derived fibroblasts In-vitro study was done to explore and evaluate the effect of shockwaves Further fibroblast cells were assessed for Cell - Cell interaction and Cell Viability
MATERIALS AND METHODS
In this in-vitro study 20 fibroblast cells were included 10 samples were considered for Control group and the remaining 10 samples were considered as Test group Extracorporeal shockwave was applied to the Test samples They were further analysed using wound scratch assay which was used to assess Cell proliferative rate and scratch closure through live imaging MTT assay and ATP assay was used to determine Cell viability after exposure to shockwaves
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None