Ignite Creation Date:
2024-05-06 @ 6:43 PM
Last Modification Date:
2024-10-26 @ 2:53 PM
Study NCT ID:
NCT05767931
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-03-14
First Post:
2023-03-01
Brief Title:
Development of Multi-specific Antibodies Based on Immune Microenvironment of Breast Cancer
Sponsor:
Peking University
Organization:
Peking University
Study Overview
Official Title:
Development of Multi-specific Antibodies Based on Immune Microenvironment of Breast Cancer
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a prospective single-center non-randomized non-controlled study
Detailed Description:
Immunotherapy with immune-checkpoint inhibitors ICIs has enabled a leap forward in the treatment of various types of cancer within the past decade Howeveronly 1246 of patients with cancer are expected to respond to ICIsOur team have recently developed a multi-specific antibody technology platform for the microenvironment of solid tumors
In this study we are going to study the tumor immune microenvironment of breast cancer patients by patient-derived organoids or PDX modelto design multi-specific antibody drugs for different tumor immune microenvironmentto look forward to improve the effectiveness of immunotherapy for breast cancer and solve the problem of drug resistance
In this study we are going to study the tumor immune microenvironment of breast cancer patients by patient-derived organoids or PDX modelto design multi-specific antibody drugs for different tumor immune microenvironmentto look forward to improve the effectiveness of immunotherapy for breast cancer and solve the problem of drug resistance
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None