Ignite Creation Date:
2024-05-06 @ 6:41 PM
Last Modification Date:
2024-10-26 @ 2:52 PM
Study NCT ID:
NCT05746052
Status:
COMPLETED
Last Update Posted:
2023-02-27
First Post:
2023-02-17
Brief Title:
Punch Elevation and Microneedling in Treatment of Atrophic Acne Scars
Sponsor:
Al-Azhar University
Organization:
Al-Azhar University
Study Overview
Official Title:
Microneedling Versus Punch Elevation With Microneedling in Treatment of Atrophic Acne Scars Comparative Study
Status:
COMPLETED
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The ultimate goal of this study was to compare punch elevation and micro needling with PRP versus micro needling and PRP only in treatment of post acne scars in an attempt to achieve better management of such condition
This is a prospective study that was carried out on 15 patients their ages ranged from 19 to 32 years with a mean of 23 years They are 6 males and 7 females 7 patients were of skin photo type III and 10 were rural residents they presented with post acne facial scars and attending the Dermatology and Andrology outpatient clinic of Al-Azhar University Hospital in Assiut between April 2021 and March 2022 Left side of face of the lesion of each patient will be treated by punch elevation two weeks before microneeedling with platlets rich plasma PRPthe right side will be treated by microneedling with PRP only from the start three sessions of microneedling will be done with 4 weeks interval
Each patient had punch elevation for scars in left side at first session then dressing removed after 7 days after three weeks all patents received treatment on both sides of the face by micro needling with PRP
During each session topical anesthesia was applied over the area of interest on face and removed after 20 mints Patients were placed in supine position with head stable the skin was stretched and micro needling was carried out in vertical horizontal and both diagonal directions for about 4-5 times PRP 2 ml were applied on the face A total of three sessions of microneedling were performed at monthly intervals
Follow-up of the patients was done before and after treatment by clinical examination and photography by comparing the photographs before and after therapy Evolution of clinical response included extent of improvement and possible adverse effects including bleeding and erythema And PIH Clinical photos of the lesions had been taken before the first session and one month after the last session and assessed clinically to grade the severity of scarring proposed by Goodman and Barons quantitative scale for acne scars at the baseline and the end of study Patients satisfaction had been done by using a quartile grading system 1 poorly satisfied 2 satisfied or 3 very satisfied
As regard efficacy of the procedures we found significant improvement of atrophic acne scars with significant reduction in number of acne scars as well as significant reduction in goodman score after treatment by punch elevation and micro needling with PRP most of patients were satisfied after treatment the side treated with punch elevation have statistically significant reduction in the number of the scar when compared to the right side
This is a prospective study that was carried out on 15 patients their ages ranged from 19 to 32 years with a mean of 23 years They are 6 males and 7 females 7 patients were of skin photo type III and 10 were rural residents they presented with post acne facial scars and attending the Dermatology and Andrology outpatient clinic of Al-Azhar University Hospital in Assiut between April 2021 and March 2022 Left side of face of the lesion of each patient will be treated by punch elevation two weeks before microneeedling with platlets rich plasma PRPthe right side will be treated by microneedling with PRP only from the start three sessions of microneedling will be done with 4 weeks interval
Each patient had punch elevation for scars in left side at first session then dressing removed after 7 days after three weeks all patents received treatment on both sides of the face by micro needling with PRP
During each session topical anesthesia was applied over the area of interest on face and removed after 20 mints Patients were placed in supine position with head stable the skin was stretched and micro needling was carried out in vertical horizontal and both diagonal directions for about 4-5 times PRP 2 ml were applied on the face A total of three sessions of microneedling were performed at monthly intervals
Follow-up of the patients was done before and after treatment by clinical examination and photography by comparing the photographs before and after therapy Evolution of clinical response included extent of improvement and possible adverse effects including bleeding and erythema And PIH Clinical photos of the lesions had been taken before the first session and one month after the last session and assessed clinically to grade the severity of scarring proposed by Goodman and Barons quantitative scale for acne scars at the baseline and the end of study Patients satisfaction had been done by using a quartile grading system 1 poorly satisfied 2 satisfied or 3 very satisfied
As regard efficacy of the procedures we found significant improvement of atrophic acne scars with significant reduction in number of acne scars as well as significant reduction in goodman score after treatment by punch elevation and micro needling with PRP most of patients were satisfied after treatment the side treated with punch elevation have statistically significant reduction in the number of the scar when compared to the right side
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None